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Gene subset selection in kernel-induced feature space
Authors:Satoshi Niijima  Satoru Kuhara  
Affiliation:

aDepartment of Bioinformatics, Graduate School of Systems Life Sciences, Kyushu University, Hakozaki 6-10-1, Higashi-ku, Fukuoka 812-8581, Japan

bFaculty of Agriculture, Kyushu University, Hakozaki 6-10-1, Higashi-ku, Fukuoka 812-8581, Japan

Abstract:This paper proposes a new filter approach to gene subset selection for kernel-based classifiers. We derive kernel forms of several well-known class separability criteria, and gene subset selection based on the kernelized criteria is applied to microarray cancer classification problems. The performance of our proposed strategy is compared in experiments with those of the conventional filter approach as well as gene ranking methods.
Keywords:Microarray   Gene selection   Cancer classification   Kernel methods
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