| 用Williamson法合成四甘醇双甲醚 |
| |
| 引用本文： | 宋庆英,吴小蓓,吴嘉武.用Williamson法合成四甘醇双甲醚[J].精细化工,2000,17(4):202-204. |
| |
| 作者姓名： | 宋庆英 吴小蓓 吴嘉武 |
| |
| 作者单位： | 中国石油化工集团公司,上海石油化工研究院,应用基础室,上海,201208 |
| |
| 摘 要： | 以四甘醇 (C8H18O5)、氯甲烷 (CH3Cl)及固体碱性氢氧化物 (MOH)为原料 ,按n (C8H18O5)∶n (CH3Cl)∶n (MOH) =1∶( 2～ 3)∶( 2～ 5) ,采用Williamson法合成四甘醇双甲醚。反应温度为55～ 90℃ ,反应压力 0 6MPa ,反应时间为 3h ,四甘醇转化率大于 99% ,双醚选择性为 78 6%。同时以四甘醇的副产四、五甘醇混合物为原料合成四、五甘醇双甲醚混合物 ,反应只需约 2h即可完成 ,双醚选择性为 93 5%。
|
| 关 键 词： | 四甘醇双甲醚 四甘醇 Williamson法 |
Synthesis of Tetraethylene Glycol Dimethyl Ether by Williamson Reaction |
| |
| SONG Qing-ying,WU Xiao-bei,WU Jia-wu.Synthesis of Tetraethylene Glycol Dimethyl Ether by Williamson Reaction[J].Fine Chemicals,2000,17(4):202-204. |
| |
| Authors: | SONG Qing-ying WU Xiao-bei WU Jia-wu |
| |
| Abstract: | Tetraethylene glycol dimethyl ether was synthesized by an improved Williamson reaction with tetraethylene glycol, methyl chloride and alkaline hydroxide at the suitable molar ratio ofn(C 8H 18 O 5)∶n(CH 3Cl)∶n(MOH)=1∶(2-3)∶(2-5). Under the pressure of 0 6 MPa, reacting for 3 h at the temperature 55-90 ℃,the conversion of tetraethylene glycol was greater than 99% and the selectivity of dimethyl ether was 786%.Moreover, the mixed tetraethylene and pentaethylene glycol dimethyl ether was synthesized with the by-product of tetraethylene glycol. The reaction was finished in about 2 h, and the selectivity of dimethyl ether was 935%. |
| |
| Keywords: | tetraethylene glycol dimethyl ether tetraethylene glycol Williamson reaction |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
