季铵盐有机硅双子表面活性剂的物理化学及抗菌性能的研究

以丙酮和正己烷为溶剂，聚乙二醇二缩水甘油醚和不同粘度羟基封端聚二甲基硅氧烷为主要原料在四丁基溴化铵（TBAB）和氢氧化钠（NaOH）的催化下合成不同硅氧链长的环氧基聚醚改性硅氧烷EP-PSix-EP(x=30，100，800)，再与N,N二甲基十二烷基叔胺在无水乙醇、盐酸催化下进行季铵化反应，制备联结基长度不同的季铵盐有机硅双子表面活性剂C12-PSix-C12（x=30，100，800)，研究C12-PSix-C12中联结基长度对其表面张力、润湿性能、乳化稳定性等物化性能及抗菌性能的影响，结果表明，随着C12-PSix-C12中联结基长度的减小，C12-PSix-C12的表面活性、乳化稳定性及润湿性能逐渐增强；抗菌实验结果显示3种表面活性剂均表现出一定的抗菌性能，且随着C12-PSix-C12中联结基长度的降低，抗菌能力增强。

Physical and Chemical Properties and Antibacterial Properties of Quaternary Ammonium Organic Silicon Gemini Surfactant

Epoxy-modified polyether ploysiloxane (EP-PSix-EP, x=30cst, 100cst, 800cst) was synthesized by ployethylene glycol diglycidyl ether and polydimethylsiloxane using TBAB and NaOH as catalyst, acetone and n-hexane as solvent. Then, quaternary ammonium organic silicon gemini surfactants (C12-PSix-C12, x=30cst, 100cst, 800cst) were synthesized by quaternarization of EP-PSix-EP with N,N-demethyldodecylaminein, in the presence of anhydrous ethanol and HCl aqueous solution. The effect of spacer length on characteristics of quaternary ammonium organic gemini surfactant was investigatedby measurement of surface activity, wettability, emulsion stabilityand antibacterial property.Experimental results showed that with decreasing of siloxane spacer length, emulsion stability and wettabilityof C12-PSix-C12 increased. Three kinds of quaternary products have antibacterial properties. Decreasing the siloxane spacer length of C12-PSix-C12, the antibacterial properties increased.