High melting lipid based approach for drug delivery: Solid lipid nanoparticles |
| |
Authors: | Sacheen Kumar Jaspreet Kaur Randhawa |
| |
Affiliation: | Centre for Material Science and Engineering, National Institute of Technology, Hamirpur 177005 (H.P), India |
| |
Abstract: | Poor solubility of newly developed drug molecules is the main problem in recent drug discovery research, so novel drug delivery approaches are being used to deliver these molecular entities for pharmacological action. Colloidal carriers (emulsion, suspensions, liposomes, polymer nanoparticles and solid lipid nanoparticles) have been used to administer poorly soluble drugs, but solid lipid nanoparticles are found to be the most reliable carriers for this type of drugs due to its advantages over other carriers. Solid lipid nanoparticles have the potential to solve the drug delivery problems with safe excipients used in its formulation. In this review all the aspects of solid lipid nanoparticles production, stability, characterization, differentiation based on route, preservation and storage have been discussed. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|