| 1,7(1,5)-二芳基庚(戊)二烯类姜黄素衍生物、类似物结构与活性的关系研究 |
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| 引用本文： | 黄可立,刘红星,黄初升,林森.1,7(1,5)-二芳基庚(戊)二烯类姜黄素衍生物、类似物结构与活性的关系研究[J].化工技术与开发,2011,40(5):17-22,12. |
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| 作者姓名： | 黄可立 刘红星 黄初升 林森 |
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| 作者单位： | 广西师范学院化学与生命科学学院,广西,南宁,530001 |
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| 基金项目： | 广西科技开发应用基础项目，广西硕士研究生科研创新计划项目 |
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| 摘 要： | 大量研究结果证明,姜黄素具有抗肿瘤,抗氧化,消炎的作用与它们的结构有密切关系,且大部分姜黄素衍生物与类似物的药理活性较姜黄素本身有所提高.这为进一步开发新的姜黄素衍生物与类似物药理功效奠定了理论基础.本文就近年来对1,7(1,5)-二芳基庚(戊)二烯类姜黄素衍生物与类似物结构的改造、修饰与其活性之间关系的研究进行探讨.
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| 关 键 词： | 姜黄素衍生物与类似物 结构改造 生物活性 |
Research in Realationgship between Structure of 1,7(1,5)-Diphenyl hepta(penta)dien Derivative from Curcumin and its Biological Activities |
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| HUANG Ke-Li,LIU Hong-Xing,HUANG Chu-Sheng,LIN Sen.Research in Realationgship between Structure of 1,7(1,5)-Diphenyl hepta(penta)dien Derivative from Curcumin and its Biological Activities[J].Technology & Development of Chemical Industry,2011,40(5):17-22,12. |
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| Authors: | HUANG Ke-Li LIU Hong-Xing HUANG Chu-Sheng LIN Sen |
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| Affiliation: | (Department of Chemistry,Guangxi Teacher Education University,Nanning 530001,China) |
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| Abstract: | Lots of research results proved that,curcumin had the activities of antitumor antioxidant,antiinflammation,which was closely related with the structure.Most compounds had better activities then curcumin.It provided a reference for further develop the pharmacological activities of curcumin and its derivatives and analogues.The link between the structure and structural modification of 1,7(1,5)-diphenyl hepta(penta)dien derivative from curcumin and its biological activities were summarized and discussed. |
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| Keywords: | curcumin derivatives and its analogues structural modification biological activities |
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