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头孢呋辛酯掩味颗粒剂的制备
引用本文:张静,吴谧,徐彦,张莉,张永祥. 头孢呋辛酯掩味颗粒剂的制备[J]. 河北化工, 2009, 32(7): 57-58
作者姓名:张静  吴谧  徐彦  张莉  张永祥
作者单位:华北制药集团新药研究开发有限责任公司,河北,石家庄,050015
摘    要:采用明胶作为主要掩昧材料,利用固体分散技术制备头孢呋辛酯颗粒剂,并进行掩味效果及稳定性考察。结果表明,该制剂口感、长期稳定性良好,是理想的临床用药。

关 键 词:头孢呋辛酯  明胶  掩味  颗粒剂

Preparation of Cefuroxime Axetil Granules for Bitter Taste Masking
ZHANG Jing,WU Mi,XU Yan,ZHANG Li,ZHANG Yong-xiang. Preparation of Cefuroxime Axetil Granules for Bitter Taste Masking[J]. Hebei Chemical Engineering and Industry, 2009, 32(7): 57-58
Authors:ZHANG Jing  WU Mi  XU Yan  ZHANG Li  ZHANG Yong-xiang
Affiliation:North China Pharmaceutical New Drug Research and Development Co.;Ltd;Shijiazhuang 050015;China
Abstract:Cefuroxime Axetil granules were prepared by solid dispersion technique with gelatin as the main materials for masking the bitter.The bitter after masking and the stability were investigated.The results showed that Cefuroxime Axetil granules had good taste and was very stable for a long term.It was feasible for the clinical application.
Keywords:Cefuroxime Axetil  gelatin  bitter taste masking  granules  
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