酶法合成生物表面活性剂

总结了外源酶催化法和整胞微生物代谢法合成生物表面活性剂的特点,并将外源酶催化法对整胞微生物代谢法及传统化学合成法的优势进行了比较.详细介绍了单甘酯、糖酯、(溶血)磷脂、纯异头烷基糖苷和氨基酸型表面活性剂等生物表面活性剂的酶催化合成方法及其研究进展;展望了酶工程的进步、化学 酶催化技术进展、外源多酶联合催化技术的开发与应用、酶膜反应器和其它连续酶反应器的开发,以及反应 分离耦合技术在酶催化过程中的应用将给酶法合成生物表面活性剂带来的机遇.

Enzymatic Synthesis of Biosurfactants

The different synthetic routes of biosurfactants by ectogenous enzymatic catalysis and metabolism of whole-cell microorganism and traditional organic synthesis were compared with one another. Some advantages of the enzymatic synthesis of biosurfactants were highlighted over the conventional organic synthesis and microorganism metabolism. Processes such as the synthesis of monoglycerides, sugar fatty acid esters, (lyso)phospholipids, alkyl glycosides and amino acid-based biosurfactants were discussed in detail. The prospect to apply enzyme in biosurfactant synthesis is expected in virtue of the advancement of enzyme engineering, chemo-enzyme catalysis, united multi-enzymes catalysis, enzyme film reactor and reaction-separation coupling technique.