新型微弧氧化钛基种植材料的细胞毒性研究

采用四甲基偶氮唑盐微量酶反应比色法（MTT法）对微弧氧化处理的钛基种植材料的细胞毒性进行研究，并用相差显微镜对细胞形态进行了观察与分析。本研究采用原代培养鉴定后的成骨细胞，与不同材料三维培养，进行种植体材料的细胞毒性研究。结果表明：微弧氧化处理的材料表面细胞形态良好，生长旺盛，细胞计数及MTT测定结果与其它组比较，具有显著性差异，细胞毒性级别优于0级，具有良好的细胞相容性。

The Cytotoxicity Study of Novel Implant Material Modified by Microarc Oxidation

Cytotoxicity of novel implant material modified by microarc oxidation technique has been investigated in this study. The cells configulation was observed on different surfaces evaluated for 2 d, 4 d and 6 d. The results showed that the cell attachment, morphology and proliferation were influenced by the different surface treatments, and a significant increase of the osteoblast cell activity was observed on the porous MAO-Ti coating. Based on these results, it was suggested that the porous MAO-Ti surface has a better biocompatibility and an excellent electrochemical performance than pure titanium surface treatments.