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有机介质中固定化酵母催化苯甲醛加氢反应
引用本文:钟春龙,梅乐和,胡方敏,郑晓冬,姚善泾.有机介质中固定化酵母催化苯甲醛加氢反应[J].浙江大学学报(自然科学版 ),2006,40(5):848-852.
作者姓名:钟春龙  梅乐和  胡方敏  郑晓冬  姚善泾
作者单位:钟春龙1,2,梅乐和1,胡方敏1,郑晓冬1,姚善泾1(1. 浙江大学 化学工程与生物工程学系
, 浙江 杭州 310027;2. 龙岩学院 化学与材料工程学系, 福建 龙岩 364000)
基金项目:中国科学院资助项目;浙江省科技计划;浙江省留学回国人员基金;教育部留学回国人员科研启动基金
摘    要:为了进一步拓展酵母在有机反应中的应用领域,考察了多种酵母在水相及有机相中对苯甲醛加氢
生成苯甲醇的催化活性,通过海藻酸钙固定化面包酵母,进一步研究了有机溶剂种类、底物初始浓度、
酵母量、酵母活化处理等因素对酵母催化苯甲醛加氢能力的影响.结果表明,假丝酵母1#和面包酵母催化
苯甲醛加氢能力较强,活化处理的酵母、较大lg P值的溶剂对催化苯甲醛加氢有较好的反应活性.本研究
为开发酵母在有机反应中的应用奠定了实验基础.

关 键 词:酵母  有机溶剂  固定化  催化加氢  苯甲醛  苯甲醇
文章编号:1008-973X(2006)05-0848-05
收稿时间:2004-12-22
修稿时间:2004年12月22

Studies on catalytic hydrogenation of benzaldehyde with immobilized yeasts in organic solvents
ZHONG Chun-long,MEI Le-he,HU Fang-min,ZHENG Xiao-dong,YAO Shan-jing.Studies on catalytic hydrogenation of benzaldehyde with immobilized yeasts in organic solvents[J].Journal of Zhejiang University(Engineering Science),2006,40(5):848-852.
Authors:ZHONG Chun-long  MEI Le-he  HU Fang-min  ZHENG Xiao-dong  YAO Shan-jing
Affiliation:1. Department of Chemical and Biochemical Engineering, Zhejiang University, Hangzhou 310027, China 2. Department of Chemistry and Material Engineering, Longyan College, Longyan 364000, China
Abstract:Catalytic hydrogenation of benzaldehyde to benzyl alcohol with a number of yeasts in aqueous phase or organic phase was investigated.The factors such as types of organic solvents,original concentration of substrates,quantity of yeasts and activating treatment of yeasts were investigated further through the baker's yeasts immobilized with calcium alginate.The results showed that catalytic hydrogenations of benzaldehyde with the candida sp and baker's yeast are relatively better,and that catalytic hydrogenations of benzaldehyde by the activated yeast and in organic solvents with higher value of lg P are preferable.This work has established the experimental foundation for applications of the yeasts in the organic reaction.
Keywords:yeasts  organic solvents  immobilization  catalytic hydrogenation  benzaldehyde  benzyl alcohol
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