Familial paraganglioma |
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Authors: | GF Murphy SD Miller DE Kenady W O'Connor DP Wood JW McRoberts WF Gee |
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Affiliation: | Division of Urology, University of Kentucky Medical Center, Lexington. |
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Abstract: | Extra-adrenal pheochromocytomas and paragangliomas are rare tumors of neural crest origin, most commonly found in the retroperitoneum. Because these tumors are so uncommon, relatively little is known about their natural history. Comparisons between adrenal pheochromocytomas and extra-adrenal pheochromocytomas have appeared in the medical literature. Like pheochromocytomas, paragangliomas may occur as functional or nonfunctional tumors. Furthermore, although the hereditary occurrence of pheochromocytomas is well documented, the familial nature of paragangliomas is unclear. We present the first report of a mother and son with nonfunctional paragangliomas occurring in the same anatomic location and describe their care and treatment. |
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