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Phosphate diesters for dermatological use
Authors:E. CARRERAS,M. CARRERAS,J. MUÑ  OZ&dagger  ,J. MALLOL&dagger  
Affiliation:Research Department, Laboratories E. Carreras, Petxina 7, Barcelona, Spain;Department of Pharmacology, School of Medicine, Badajoz, Spain.
Abstract:A new formulation for dermatological use and hair care was studied. Phosphate diesters of the nonyl-phenol type in association with cocoimidazoline derivatives are compared with four commercial formulations. Foaming capacity, eye and skin irritation, keratin solubilization and defatting properties were studied. The mixture was the best foamforming formulation and the best defatting agent. Also, it was non-irritant for skin and eyes at adequate dilutions and did not dissolve keratin. It is a good formulation for dermatological use and hair care, due to its detergent properties. It ranks high among safe products.
Di-ésters phosphates à usage dermatologique
Keywords:phosphate diesters    cocoimidazoline derivatives
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