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The IVAIRE project – a randomized controlled study of the impact of ventilation on indoor air quality and the respiratory symptoms of asthmatic children in single family homes
Authors:P. Lajoie  D. Aubin  V. Gingras  P. Daigneault  F. Ducharme  D. Gauvin  D. Fugler  J.‐M. Leclerc  D. Won  M. Courteau  S. Gingras  M.‐È. Héroux  W. Yang  H. Schleibinger
Affiliation:1. Environmental Health and Toxicology Division, Institut national de santé publique du Québec (INSPQ), Quebec City, QC, Canada;2. NRC Construction, National Research Council of Canada, Ottawa, ON, Canada;3. Department of Pediatrics, Mother Child Centre, Québec University Hospital Centre (CHUQ), Quebec City, QC, Canada;4. Department of Pediatrics and of Social and Preventive Medicine, Sainte‐Justine University Hospital Centre, Université de Montréal, Montréal, QC, Canada;5. Formerly with Policy and Research, Canada Mortgage and Housing Corporation (CMHC), Ottawa, ON, Canada;6. Health Canada, Air Health Effects Division, current affiliation with World Health Organization, European Centre for Environment and Health, Bonn, Germany
Abstract:A randomized controlled trial was carried out to measure the impact of an intervention on ventilation, indoor air contaminants, and asthma symptoms of children. Eighty‐three asthmatic children living in low‐ventilated homes were followed over 2 years. Several environmental parameters were measured during the summer, fall, and winter. The children were randomized after Year 1 (43 Intervention; 40 Control). The intervention included the installation of either a Heat Recovery Ventilator (HRV) or Energy Recovery Ventilator (ERV). During the fall and winter seasons, there was a significant increase in the mean ventilation rate in the homes of the intervention group. A statistically significant reduction in mean formaldehyde, airborne mold spores, toluene, styrene, limonene, and α‐pinene concentrations was observed in the intervention group. There was no significant group difference in change in the number of days with symptoms per 14 days. However, there was a significant decrease in the proportion of children who experienced any wheezing (≥1 episode) and those with ≥4 episodes in the 12‐month period in the intervention group. This study indicates that improved ventilation reduces air contaminants and may prevent wheezing. Due to lack of power, a bigger study is needed.
Keywords:Asthma  Children  Respiratory symptoms  Field study  Ventilation  Indoor air  Home
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