动物源性降糖肽的研究进展

一些食源性活性肽降糖效果显著，具有开发成功能性食品的潜力，在世界范围内引起广泛关注。其中广泛存在于食物蛋白水解物中的动物源性活性肽具有较好的降血糖特性，其潜在机制包括抑制α-葡萄糖苷酶或二肽基肽酶-4(dipeptidyl peptidase-4，DPP-4)等。本文介绍了动物源性降糖肽的制备方法、作用机理及降糖效果的评价方法，重点综述了来源于畜禽肉、鱼类、血液、乳类和蛋类等动物性食物的降糖肽的现有研究成果，为预防和辅助治疗糖尿病及相关功能性食品的开发提供了理论依据。

Research Progress of Animal-derived Hypoglycemic Peptides

Some food-derived active peptides have significant hypoglycemic effects and have the potential to be developed into functional foods, which has attracted attention worldwide. Among them, animal-derived active peptides in food protein hydrolysates have hypoglycemic properties, and their potential mechanisms include inhibition of α-glucosidase or dipeptidyl peptidase-4 (DPP-4). In this paper, the preparation method, the mechanism of action and the evaluation method of the hypoglycemic effect of animal-derived hypoglycemic peptides are introduced, and antiglycemic peptides derived from animal foods such as livestock and poultry meat, fish, blood, milk and eggs are reviewed, which provides a theoretical basis for the prevention and adjuvant therapy of diabetes and the development of related functional foods.