食药用菌多糖经由肠道菌群调节脂质代谢的研究进展

肥胖和高血脂症已成为当今社会严重的公共卫生问题。研究发现食药用菌多糖可以通过促进肠道内益生菌的增殖、抑制有害菌的生长，改善肠道菌群，发挥脂质代谢的调节作用，但目前，其调节脂质代谢的具体机理还未能确定和统一。本文主要围绕食药用菌多糖、肠道菌群、脂质代谢三者之间的相互联系及其作用，以及食药用菌多糖经肠道菌群调节脂质代谢可能的机理，主要包括短链脂肪酸合成途径和减少炎症反应进行了综述，并讨论了食药用菌多糖经肠道菌群调节脂质代谢现有研究的不足之处及未来的发展方向，旨在为食药用菌活性成分的利用及营养功能性食品的研发提供参考。

Research Progress of Polysaccharides from Edible and Medicinal Fungi in Regulating Lipid Metabolism through Gut Microbiota

Obesity and hyperlipidemia have become serious public health problems in today's society. Studies have found that edible and medicinal fungi polysaccharides can promote the proliferation of probiotics in the intestines, inhibit the growth of harmful bacteria, improve the intestinal flora, and play a role in regulating lipid metabolism. But at present, its specific mechanism has not been determined and unified in regulating lipid metabolism. This article mainly focused on the interaction and effects between polysaccharides of edible and medicinal bacteria, gut microbiota and lipid metabolism, as well as the possible mechanism of edible and medicinal fungi polysaccharides in regulating lipid metabolism through gut microbiota, mainly including the short-chain fatty acid pathway and the activity of reducing inflammation are reviewed. The aim of this study would provide a reference for the utilization of active ingredients of edible and medicinal fungi and the research and development of nutritional functional foods.