肠类器官应用于营养素吸收的研究进展

肠道不仅是营养物质消化吸收的主要部位，也是重要的免疫器官和内分泌器官。营养物质在肠道内的消化吸收状况是决定其高效利用的重要因素。构建适宜的体外肠道模型对明确营养物质的有效吸收部位、吸收效率及机制具有重要意义。类器官由于可高度模拟目标组织或器官的遗传特性和表观特征被广泛应用于各个领域。本文综述了近年来肠类器官在营养物质消化吸收方面的研究进展，以期为肠类器官在营养物质的消化吸收中的广泛应用提供参考。

Application Research Progress of Intestinal Organoids in Nutrient Absorption

The intestinal tract is not only the main part of nutrient digestion and absorption, but also an important immune and endocrine organ. The digestion and absorption of nutrients in the intestine is a crucial factor to achieve their efficient utilization. Constructing an appropriate in vitro intestinal model is of great significance to clarify the effective absorption site, absorption efficiency, and mechanism of nutrients. Organoids are widely used in various fields because they can highly simulate the genetic and apparent characteristics of target tissues or organs. This paper reviews the recent application research progress of intestinal organoids in nutrient digestion and absorption, with a view to providing a reference for the wide application of intestinal organoids in nutrient digestion and absorption.