乳酸菌高密度培养技术的研究进展

乳酸菌对人类生活大有裨益，是工商业生产中极为重要的研究对象。乳酸菌高密度培养是其工业化应用的重要步骤。乳酸菌高密度培养可以较低的培养体积和较短的培养周期获得较高的菌体密度，提高发酵速度和发酵效果，应用于生产实践中能够减少后续发酵剂的使用量，并控制设备投资，降低生产成本。乳酸菌高密度培养受到生产菌株、培养基成分、发酵条件以及发酵模式等因素的影响。本文主要从乳酸菌高密度培养的营养消耗模式、培养基、培养条件、培养技术等方面进行综述，并展望了今后的研究方向，以期为乳酸菌发酵剂的高效制备及工业应用提供理论依据。

Research Progress of Lactic Acid Bacteria High-density Culture Technology

Lactic acid bacteria are of great benefit to human life and are extremely important research objects in industrial and commercial production. High-density culture of lactic acid bacteria is an important step for its industrial application. High-density culture of lactic acid bacteria can obtain higher bacterial density with lower culture volume and shorter culture cycle, improve fermentation speed and fermentation effect, and reduce the subsequent use of starter, control equipment investment and reduce production cost in production practice. High-density culture of lactic acid bacteria is affected by factors such as production strains, medium, fermentation conditions, and fermentation modes. This paper mainly reviewed nutrient consumption mode, medium, culture condition, culture technology from high-density culture of lactic acid bacteria. Finally, the future research directions were prospected, in order to provide theoretical basis for the efficient preparation and industrial application of lactic acid bacteria starter.