| 抗菌肽的结构功能关系及分子设计的研究现状 |
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| 引用本文： | 潘婕,高振珅,叶增民. 抗菌肽的结构功能关系及分子设计的研究现状[J]. 广东化工, 2011, 38(12): 58-59 |
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| 作者姓名： | 潘婕 高振珅 叶增民 |
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| 作者单位： | 1. 中北大学化工与环境学院,山西太原,030051
2. 临沂大学生命科学学院,山东临沂,276005 |
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| 摘 要： | 抗菌肽是一种广泛存于自然界中具有广谱抗菌作用的小分子多肽。文章首先对抗菌肽的结构进行分类、从肽链长度、α-螺旋结构、疏水性、两亲性和净电荷5个方面分析了分子结构对活性的影响、并对抗菌肽的分子设计进行了综述,对其发展前景进行了展望。
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| 关 键 词： | 抗菌肽 结构 分子设计 |
Current Status of Relationship between Antimicrobial Peptide Structure and Function as well as Its Molecular Design |
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| Pan Jie,Gao Zhenshen,Ye Zengmin. Current Status of Relationship between Antimicrobial Peptide Structure and Function as well as Its Molecular Design[J]. Guangdong Chemical Industry, 2011, 38(12): 58-59 |
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| Authors: | Pan Jie Gao Zhenshen Ye Zengmin |
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| Affiliation: | 1(1.School of Chemical Engineering and Environment,North University of China,Taiyuan 030051; 2.College of Life Science,Linyi University,Linyi 276005,China) |
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| Abstract: | Antimicrobial peptides are one kinds of small molecular polypetides with its broad spectrum and activities against bacteria.In the paper,Classification the structure of antimicrobial peptides,Analysis the molecular structure of activity from chain length,α-helix structure,hydrophobicity,amphiphilic net charge and reviewed the molecular design of antimicrobial peptide as well as its prospect. |
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| Keywords: | antimicrobial peptide structure molecular design |
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