食源性生物活性肽免疫调节功能研究进展

食源性生物活性肽是一种以食源性蛋白为原料,经过水解及分离纯化后得到的具有特殊生物活性的蛋白水解物,其氨基酸残基数目不等且相对分子质量一般较小。食源性免疫活性肽为一类具有抗菌、抗炎以及调节免疫系统功能的生物活性肽,其来源广、活性高,极具研究意义。文章综述了近年来食源性免疫活性肽的研究现状及其对免疫系统的影响,介绍了食源性免疫活性肽的制备方法,并从免疫活性肽功能多样性、构效关系与制备关键技术三方面对食源性免疫活性肽的研究趋势进行了展望。

Research progress in immune regulation of food-derived bioactive peptides

Food derived bioactive peptides are a series of specific functional hydrolysates of food proteins with relatively small molecular weight, containing deferent number of amino acid residues. And food-derived immunoactive peptides are those bioactive ones that play important roles on antibacterial, anti-inflammatory, and immunoregulation. Thus it is significant to investigate them because of their wide distribution and high bioactivities. The recent research status and the immune functions of immunopeptides are summarized. Moreover, some methods of producing immunoactive peptides were also introduced. Finally it is prospected that the research tendency of the immunoregulatory mechanism of immune peptides and their advanced utilization.