复合配方软胶囊人体抗氧化功能试食效果评价

目的:评价复合配方软胶囊人体抗氧化功能试食效果。方法:将120例志愿者随机分为试食组和对照组,试食组给予复合配方软胶囊90 d,对照组服用安慰剂,采用自身及组间对照方法,实验前后各进行一次相关安全性指标及功效指标的测定。结果:试食后试食组超氧化物歧化酶升高14.69±18.51 U/m L,上升率为19.55%,自身及组间比较的差异有统计学意义(p<0.05);丙二醛降低1.67±3.03 nmol/m L,下降率为14.97%,自身及组间比较的差异有统计学意义(p<0.05);谷胱甘肽过氧化物酶升高5.73±29.64 U/m L,上升率为5.29%,自身及组间比较的差异无统计学意义,对照组三项指标变化均不明显。试食前后各项安全性指标均无明显变化,说明受试物对受试者身体健康无不良影响。结论:此复合配方软胶囊对人体具有抗氧化功能。 

Evaluation of anti- oxidation function of compound formula soft capsule on human using eating test

Objective: To evaluate the impact of complex formula soft capsule's anti-oxidation function on human body after human test.Methods: 120 volunteers were randomly divided into test group and control group.Subjects in test group were given complex formula of soft capsules consecutively for 90 days.The control group takes the placebo.Using methods of self-control and the control group,indicators related safety and efficacy parameters were measured.Results: After eating complex formula of soft capsules,superoxide dismutase( SOD) of test group increased 14.69 ± 18.51 U/m L,which increased the percentage of 19.55%,there was significant difference in selfcontrol and the control group. Malondialdehyde( MDA) was reduced 1.67 ± 3.03 nmol/m L,the percentage of decreasing level was 14.97%,there was significant difference in self-control and the control group. Glutathione peroxidase( GSH-PX) increased 5.73 ± 29.64 U/m L,the percentage of was 5.29%,there was no significant difference between self-control and the control group. Before and after the testing,there were not significantly change about every safe index. The above showed that the product had no adverse effects on the subject 's health.Conclusions: The complex formula of soft capsules has anti-oxidation function.