| 柚皮苷二氢查耳酮工艺研究 |
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| 引用本文： | 罗春,黄建军,杨柳.柚皮苷二氢查耳酮工艺研究[J].精细化工中间体,2011,41(4):62-65. |
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| 作者姓名： | 罗春 黄建军 杨柳 |
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| 作者单位： | 广州汉方现代中药研究开发有限公司,广东广州,510970 |
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| 摘 要： | 以柚皮苷为原料制备了柚皮苷二氢查耳酮。考察了反应时间、催化剂用量、反应温度、反应压力、搅拌速度等因素对柚皮苷二氢查耳酮收率的影响。实验结果表明,制备柚皮苷二氢查耳酮优化反应条件为:pH值为13,反应温度45℃,反应时间6 h,氢气压力0.5 MPa,雷尼镍(用量为柚皮苷质量的7%)为催化剂,此条件下收率达90.0%。
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| 关 键 词： | 柚皮苷 柚皮苷二氢查耳酮 催化氢化 雷尼镍 |
Study on Preparation of Naringin Dihydrochalcone |
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| LUO Chun,HUANG Jian-jun,YANG Liu.Study on Preparation of Naringin Dihydrochalcone[J].Fine Chemical Intermediates,2011,41(4):62-65. |
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| Authors: | LUO Chun HUANG Jian-jun YANG Liu |
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| Affiliation: | LUO Chun,HUANG Jian-jun,YANG Liu(Guangzhou Hanfang Pharmaceutical Co.,Ltd.,Guangzhou 510970,China) |
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| Abstract: | The process for preparation of naringin dihydrochalcone from naringin was investigated.The product was obtained in 90% yield under optimum conditions of pH 13,temperature 45℃,H2 pressure 0.5 MPa,raney nickel loading 5%,and reaction time 4 h. |
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| Keywords: | naringin naringin dihydrochalcone catalytic hydrogenation raney nickel |
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