Electrochemical behavior of folic acid on mercury meniscus modified silver solid amalgam electrode

Voltammetric behavior of folic acid and folates has been investigated using direct current voltammetry, differential pulse voltammetry and adsorptive stripping differential pulse voltammetry at a mercury meniscus modified silver solid amalgam electrode (m-AgSAE). The optimum conditions have been found for their determination in a 1:9 mixture of methanol and aqueous acetate buffer, with the limit of detection about 0.5 nmol L⁻¹. RSD at this concentration level amounted to less than 4%. Practical applicability of the newly developed method was verified by analysis of three vitamin preparations and of two multivitamin juices.