Synthesis and in vitro anthelmintic activity against Nippostrongylus brasiliensis of new 2-amino-4-hydroxy-delta-valerolactam derivatives |
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| Authors: | S Gordon L Costa M Incerti E Manta J Salda?a L Domínguez R Mariezcurrena L Suescun |
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| Affiliation: | Cátedra de Química Farmacéutica, Fac. de Química, Universidad de la República, Montevideo, Uruguay. |
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| Abstract: | The synthesis of a series of 2-amino-4-hydroxy-delta-valerolactam derivatives is described (compounds 4 to 10). These compounds showed a high anthelmintic in vitro activity against the Nippostrongylus brasiliensis model. |
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