| 聚氨酯/硫酸酯化壳聚糖复合膜的制备及其血液相容性的研究 |
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| 引用本文： | 周素琼,李国明. 聚氨酯/硫酸酯化壳聚糖复合膜的制备及其血液相容性的研究[J]. 化工时刊, 2007, 21(5): 1-4 |
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| 作者姓名： | 周素琼 李国明 |
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| 作者单位： | 华南师范大学化学与环境学院,广东,广州,510006;华南师范大学化学与环境学院,广东,广州,510006 |
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| 摘 要： | 用6-O-硫酸酯化壳聚糖(6S-CS)与水性聚氨酯(WPU)混和,以戊二醛作交联剂,制备出WPU/6S-CS复合膜。通过红外和偏光显微镜测试技术对复合膜的结构和形态进行表征,并通过溶血实验、动态凝血时间、复钙化时间等对其血液相容性进行了表征。研究结果表明WPU/6S-CS复合膜具有较好的血液生物相容性是一种理想的生物医用材料。
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| 关 键 词： | 壳聚糖 水性聚氨酯 半互穿网络结构 血液相容性 |
| 收稿时间： | 2007-01-04 |
| 修稿时间： | 2007-01-04 |
Synthesis and Blood Compatibility of WPS/6CS Composite Membranes |
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| Zhou Suqiong,Li Guoming. Synthesis and Blood Compatibility of WPS/6CS Composite Membranes[J]. Chemical Industry Times, 2007, 21(5): 1-4 |
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| Authors: | Zhou Suqiong Li Guoming |
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| Affiliation: | College of Chemistry and Environmental Science, South China Norm at University, Guangdong Guangzhou 510006 |
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| Abstract: | Novel semi-interpenetrating polymer network(senfi-lPN) membranes were synthesized from 6-O-sulfochitosan(6S-CS) and waterborne polyurethanes(WPU) with ether soft segments,using glutaraldehyde as the cross-linking agent.The structure and morphologies of the composite membranes have been characterized by infrared spectroscopy(IR) and optical polarization micrograph(OPM).The hemolysis,recalification time and dynamic blood-clotting tests were used to characterize the blood compatibility of composite membrane.The result showed that file composite membrane had good blood compatibility,and they could be good biomedical materials. |
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| Keywords: | chitosanwaterborne polyurethanesewi-interpenetrating polymer networksblood compatibility |
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