| 均匀设计优化党参多糖硫酸酯合成工艺 |
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| 引用本文： | 王毅,程亮,余兰.均匀设计优化党参多糖硫酸酯合成工艺[J].食品科技,2012(10):168-170. |
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| 作者姓名： | 王毅 程亮 余兰 |
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| 作者单位： | 遵义医学院药学院 |
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| 基金项目： | 贵州省科技厅2007年科研攻关计划项目(黔科合S字(2007)1043) |
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| 摘 要： | 用氨基磺酸法对党参多糖进行硫酸化修饰,采用均匀设计U8(43)对党参多糖硫酸酯化工艺进行优化设计,并用氯化钡-明胶法测定硫酸根的取代度。确定了党参多糖硫酸酯化最佳工艺条件:温度为60℃、时间15min、投料比为1:0.04(g/mol)。此种方法能够为多糖硫酸化的进一步研究提供研究参数。
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| 关 键 词： | 党参多糖 多糖硫酸酯 均匀设计 |
Optimization sulfate of Codonopsis pilosula polysaccharide by uniform-design method |
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| WANG Yi, CHENG Liang, YU Lan.Optimization sulfate of Codonopsis pilosula polysaccharide by uniform-design method[J].Food Science and Technology,2012(10):168-170. |
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| Authors: | WANG Yi CHENG Liang YU Lan |
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| Affiliation: | * (Pharmacy School, Zunyi Medical College, Zunyi 563003) |
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| Abstract: | Codonopsis pilosula polysaccharide (CPPS) was modified by sulfamic acid. Uniform-design method U8 (43) was used, taking substitution degee and productivity as index. It showed that the reaction temperature of 60℃, reaction time of 15 min and condition with 0.04 mol. It provides valuable parameters for further studies on structure-activity ralationship of CPPS and S-CPPS. |
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| Keywords: | Codonopsis pilosula polysaccharides(CPPS) sulfated polysaccharide uniform-design method |
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