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元胞自动机图的蛋白质二级结构类型预测
引用本文:胡鸿豪,宋丽平,肖绚.元胞自动机图的蛋白质二级结构类型预测[J].计算机工程与应用,2010,46(15):226-229.
作者姓名:胡鸿豪  宋丽平  肖绚
作者单位:景德镇陶瓷学院 机电学院,江西 景德镇 333001
基金项目:国家自然科学基金No.60661001;;江西省自然科学基金No.0611060~~
摘    要:蛋白质结构预测是后基因组时代的一项重要任务,蛋白质二级结构预测是蛋白质结构预测的关键步骤。利用氨基酸数字编码模型生成蛋白质序列的元胞自动机图(Cellular Automata Image,CAI),提出了一种基于灰度共生矩阵(Gray Level Co-occurrence Matrix,GLCM)提取纹理图像特征的方法。用扩大的协方差算法进行预测,仿真结果显示有较好的分类效果,Jackknife检验的预测成功率达到94.61%。

关 键 词:蛋白质二级结构  元胞自动机  灰度共生矩阵  K近邻算法  Jackknife测试
收稿时间:2008-11-16
修稿时间:2009-2-9  

Secondary structure prediction by GLCM of CAI
HU Hong-hao,SONG LI-ping,XIAO Xuan.Secondary structure prediction by GLCM of CAI[J].Computer Engineering and Applications,2010,46(15):226-229.
Authors:HU Hong-hao  SONG LI-ping  XIAO Xuan
Affiliation:Jingdezhen Ceramic Institute,Jingdezhen,Jiangxi 333001,China
Abstract:One of the important tasks of the post genome project is protein structure prediction,the key step of which is protein secondary structure prediction.This paper makes use of a model of digital coding for amino acid,and uses cellular automata to generate image representation for protein sequences.A protein sequence can be represented by a unique image,and the image takes into account the interactional actions between amino acids.By the Gray Level Co-occurrence Matrix(GLCM) deriving from the CAI,a novel metho...
Keywords:secondary structure prediction  Cellular Automata(CA)  Gray Level Co-occurrence Matrix(GLCM)  K nearest neighbor algorithm  Jackknife cross-validation
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