Evaluation of wool nanoparticles incorporation in chitosan/gelatin composite films |
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| Authors: | Niloofar Eslahi Fatemeh Dadashian Nahid Hemmati Nejad Mohammad Rabiee |
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| Affiliation: | 1. Department of Textile Engineering, Amirkabir University of Technology, Tehran, Iran;2. Center of Excellence on Functional Fibrous Structures and Environmental Enhancement, Amirkabir University of Technology, Tehran, Iran;3. Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran |
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| Abstract: | The aim of this work was to develop chitosan/gelatin composite films embedded with various amounts of wool nanoparticles, which were produced by an environmental friendly process. Films loaded with wool nanoparticles were subjected to physiochemical, biological, and mechanical characterization. The obtained results showed that incorporation of wool nanoparticles into chitosan/gelatin composite led to a reduction in swelling, moisture content and dissolution degree of the films. In vitro degradation test revealed that the nanoparticles‐embedded composites had a lower degradation rate than that of chitosan/gelatin composite. Besides, composite films containing wool nanoparticles showed an improvement in the stability in phosphate buffered saline. On the other hand, tensile strength and elongation at break decreased upon loading the films with wool nanoparticles. The biocompatibility of the produced composites was also confirmed by MTT test. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131, 40294. |
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| Keywords: | biopolymers and renewable polymers properties and characterization biomaterials biodegradable biocompatibility |
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