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高含量β-胡萝卜素微胶囊干粉流动性的考察及其影响因素
引用本文:许新德,姚善泾,韩宁,邵斌.高含量β-胡萝卜素微胶囊干粉流动性的考察及其影响因素[J].中国化学工程学报,2007,15(4):579-585.
作者姓名:许新德  姚善泾  韩宁  邵斌
作者单位:[1]Department of Chemical and Biochemical Engineering, Zhejiang University, Hangzhou 310027, China [2]Xinchang Pharma. Factory, Zhejiang Medical Co. Ltd., Xinchang 312500, China
基金项目:Supported by the National-Natural Science Foundation of China (No.20576118) and National High Technology Research and Development Program of China (863 Program, No.2006AA02Z210).
摘    要:The flowability of five kinds of microencapsulation powders, with different β-carotene contents and by two alternative particle-forming technologies i.e. spray-drying and starch-catching beadlet technology, was measured. The actual flow properties of the five powders were compared based on bin-flow test, and three flow indexes (Hausner ratio, repose angle and flow index) were measured. It was found that the repose angle is the most suitable index to reflect the flowability of these powders for the particle properties would not be altered due to compaction or tapping during the measuring process. Particle size and particle size distribution play most important roles in the flowability of these granular materials, which was also influenced by other factors like shape, surface texture, surface roughness, etc. Microcapsules with wall material of gelatin and a layer of modified starch absorbed on the surface showed excellent flowabilities and good mechanical properties, and they are favorable for tabletting to supply β-carotene.

关 键 词:微囊剂粉体  流动性  胡萝卜素B  豪斯纳尔理论  静安息角
收稿时间:11 May 2006
修稿时间:2006-05-11

Measurement and Influence Factors of the Flowability of Microcapsules with High-content β-Carotene
XU Xinde,YAO Shanjing,HAN Ning,SHAO Bin.Measurement and Influence Factors of the Flowability of Microcapsules with High-content β-Carotene[J].Chinese Journal of Chemical Engineering,2007,15(4):579-585.
Authors:XU Xinde  YAO Shanjing  HAN Ning  SHAO Bin
Affiliation:Department of Chemical and Biochemical Engineering, Zhejiang University, Hangzhou 310027, China Xinchang Pharma. Factory, Zhejiang Medical Co. Ltd., Xinchang 312500, China
Abstract:
Keywords:β  -carotene  microcapsule powders  flowability  Hausner ratio  repose angle
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