Torsades de pointes with terfenadine ingestion |
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Authors: | RA June I Nasr |
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Affiliation: | Department of Emergency Medicine, Cook County Hospital, Chicago, IL 60612, USA. |
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Abstract: | Torsades de pointes (TDP) is a ventricular tachycardia that can deteriorate into ventricular fibrillation. TDP has been associated with terfenadine use in cases of liver disease, electrolyte abnormalities, concomitant administration of drugs that inhibit cytochrome P-450, or deliberate overdose. This report describes the first case of TDP in a healthy patient taking the recommended therapeutic dosage of terfenadine. |
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