The chemistry of lipid peroxidation metabolites: Crosslinking reactions of malondialdehyde |
| |
| Authors: | Nair Vasu Cooper Curt S. Vietti David E. Turner Gregory A. |
| |
| Affiliation: | (1) Department of Chemistry, University of Iowa, 52242 Iowa City, IA |
| |
| Abstract: | Malondialdehyde reacts readily with amino acids to form adducts containing vinylogous amidine linkages. Crosslinking reactions between nucleic acid bases, and amino acids induced by malondialdehyde also have been investigated. The physical data obtained for the adducts provide structural information on the possible mode of crosslinking of proteins and nucleic acids induced by this lipid metabolite. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
