摇瓶反应器中流体流动的CFD数值模拟

针对250 ml摇瓶在回转式摇床上的流体流动，基于VOF模型、RNG k-ε湍流模型结合建立了描述摇瓶液体的流体动力学模型，并利用计算流体力学软件FLUENT和动网格技术对其进行了数值模拟。考察了不同转速和不同装液量条件的摇瓶内液体的流动状态，液相形状变化，液面高度，气液接触面积，液体总表面积的变化。模拟计算结果给出不同操作条件对湍流参数（湍流强度、湍动能、湍动能耗散率）和溶氧传质系数的影响，获得了湍动能耗散率与摇瓶转速和装液量之间的关联式。

Numerical simulation Of fluid flow in Erlenmeyer shake flask with computational fluid dynamics

A fluid dynamics model of volume of fluid（VOF）was proposed to simulate the flow behavior in an Erlenmeyer shake flask with a volume of 250 ml liquid in combination with the RNG k-ε turbulence model.The numerical simulation was carried out by using a commercial computational fluid dynamics software，FLUENT，with the dynamic mesh（DM）technique.The effects of operation conditions of 5 different rotation speeds and 3 liquid loading volumes on the flow including liquid shape，height of liquid surface，gas-liquid interfacial area and the total surface area of liquid were investigated in the simulation.The effects of operation conditions on turbulent parameters（e.g.turbulent intensity，turbulent kinetic energy and turbulent dissipation rate），and on oxygen liquid-phase mass transfer coefficient，were also discussed.The results suggested that the parameters correlated to liquid shape were significantly influenced by rotation speed（N），and that the values of turbulent parameters increased with the increase of rotation speed（N），and decreased with the increase of liquid loading volume（V）in flask.The correlation between ε and N with V was obtained by non-linear regression.