催化合成L-抗坏血酸棕榈酸酯的反应媒体和脂肪酶

对水、庚烷和叔戊醇等几种反应媒体和NOVO4 3 5(Candidaantartica) ,MML (Mucormiehei) ,LIPOLASE ,PPL(Porcinepancreas)等数种脂肪酶对L 抗坏血酸棕榈酸酯合成反应的影响进行了系统的研究 .结果表明 ,反应媒体及脂肪酶品种对反应影响极大 .所研究的几种反应媒体中 ,叔戊醇是唯一适用于该反应的反应媒体 .在所研究的几种脂肪酶中 ,NOVO 4 3 5表现出了良好的催化活性 ;MML也有一定活性 ,但不如NOVO 4 3 5,其相对活力只有NOVO 4 3 5的 2 0 % ,其余酶种则无催化活性 .

Selection of Suitable Reaction Media and Lipase:Synthesize of L-ascorbyl Palmitate Catalyzed by Lipase

The influences of reaction media including water, heptane and 2 methyl 2 butanol as well as the kinds of lipase such as NOVO435, MML, LIPOLASE, PPL on the synthesize of L ascorbyl palmitate catalyzed by lipase has been investigated in detail. It is indicated that the kind of reaction media as well as lipase can influence such reaction significantly. As the conclusion, 2 methyl 2 butanol is the only suitable reaction media among the media investigated in this paper. NOVO 435 is the best one fitting for the reaction among the lipases investigated in this paper.