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灵芝孢子醇提取液的体外抗肿瘤活性
引用本文:杨新林,朱鹤孙,徐建兰,匡群. 灵芝孢子醇提取液的体外抗肿瘤活性[J]. 北京理工大学学报(英文版), 1997, 6(4): 336-340
作者姓名:杨新林  朱鹤孙  徐建兰  匡群
作者单位:北京理工大学材料科学研究中心,中国无锡三联高科技开发公司
摘    要:利用几种来源于人或小鼠的癌细胞系(包括上皮癌细胞和白血病细胞)和MTT法,探讨灵芝孢子醇提取液是否具有体外抗肿瘤活性,并对破壁与不破壁孢子粉醇提取液对癌细胞作用的差异进行比较发现破壁与不破壁孢子粉醇提取液均能显著抑制癌细胞的增殖,而破壁孢子粉醇提取液比不破壁孢子粉醇提取液作用更明显结果提示灵芝孢子在肿瘤治疗方面可能有较好的应用前景

关 键 词:灵芝孢子;醇提取液;抗肿瘤活性;癌细胞系

Antitumor Activity of the Ganoderma Lucidum Spore Alcohol Extract in Vitro
Yang Xinlin,Zhu Hesun,Xu Jianlan and Kuang Qun. Antitumor Activity of the Ganoderma Lucidum Spore Alcohol Extract in Vitro[J]. Journal of Beijing Institute of Technology, 1997, 6(4): 336-340
Authors:Yang Xinlin  Zhu Hesun  Xu Jianlan  Kuang Qun
Affiliation:Center for Research on Materials Science,Beijing Institute of Technology,Beijing 100081;Center for Research on Materials Science,Beijing Institute of Technology,Beijing 100081;China Wuxi Sanlian Advanced Science & Technology Development Co.Ltd,Wuxi 214021;China Wuxi Sanlian Advanced Science & Technology Development Co.Ltd,Wuxi 214021
Abstract:Several cancer cell lines(epithelioma cells or leukemia cells)from human being or mouse were first used to study the antitumor activity of the Ganoderma lucidum spore alcohol extract(GLSAE)in vitro by the MTT test A comparision was made between the sporodermbroken(SB)and sporoderm nonbroken(SN)GLSAE It was showed that both GLSAE SB and GLSAE SN could inhibit the proliferation of these cancer cells,but the activity of GLSAE SB was much higher than that of GLSAE SN These results suggested that Ganoderma lucidum spore could probably be used for tumor treatment
Keywords:Ganoderma lucidum spore  alcohol extract  antitumor activity  cancer cell line
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