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Synthesis and antitumor activity of 4-[p-[bis(2-chloroethyl)amino]phenyl]butyrates |
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| Authors: | GR Roehrig JH Billman J Marcec P Fritz F Shea |
| Abstract: | Ten 4-p-bis(2-chloroethyl)amino]phenyl]butyrates were synthesized and evaluated for antitumor activity. The 2-phenoxyethyl ester exhibited activity against P-388 lymphocytic leukemia, and the n-butyl and n-pentyl esters exhibited activity against L-1210 lymphoid leukemia in initial screening tests. |
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