| 还原烷基化法制备间-(N,N-二乙基氨基)-乙酰苯胺 |
| |
| 引用本文： | 王瑞灵,陈永杰,曹爽,张芮. 还原烷基化法制备间-(N,N-二乙基氨基)-乙酰苯胺[J]. 精细石油化工, 2019, 36(3): 13-16 |
| |
| 作者姓名： | 王瑞灵 陈永杰 曹爽 张芮 |
| |
| 作者单位： | 沈阳化工大学应用化学学院,辽宁沈阳,110142;沈阳化工大学应用化学学院,辽宁沈阳,110142;沈阳化工大学应用化学学院,辽宁沈阳,110142;沈阳化工大学应用化学学院,辽宁沈阳,110142 |
| |
| 摘 要： | 以间苯二胺和冰乙酸为原料,经乙酰化反应合成间乙酰氨基苯胺,间乙酰氨基苯胺再与乙醛缩合,以三乙酰氧基硼氢化钠为还原剂进行还原,制备了间-(N,N-二乙基氨基)-乙酰苯胺。采用TLC对反应进程进行监测,柱层析法对产物进行分离提纯,通过FT-IR、1HNMR、LCMS对产物进行了表征。
|
| 关 键 词： | 间苯二胺 间乙酰氨基苯胺 乙醛 三乙酰氧基硼氢化钠 间-(N,N-二乙基氨基)-乙酰苯胺 |
SYNTHESIS OF m-(N,N-DIETHYLAMINO)-ACETANILIDE BY REDUCTIVE ALKYLATION REACTION |
| |
| Wang Ruiling,Chen Yongjie,Cao Shuang,Zhang Rui. SYNTHESIS OF m-(N,N-DIETHYLAMINO)-ACETANILIDE BY REDUCTIVE ALKYLATION REACTION[J]. Speciality Petrochemicals, 2019, 36(3): 13-16 |
| |
| Authors: | Wang Ruiling Chen Yongjie Cao Shuang Zhang Rui |
| |
| Affiliation: | (Shenyang University of Chemical Technology,Shenyang 110142,Liaoning,China) |
| |
| Abstract: | m-Acetaminoaniline was prepared by acetylation using m-Phenylenediamine and acetic acid as raw materials, then m -acetamidoaniline condensed with acetaldehyde, followed by reduction with sodium triacetoxyborohydride as reducing agent, to prepare m -(N,N-diethylamino)-acetanilide. The reaction process was monitored by TLC, and the product was puryfied with the means of column chromatography. The structure of products were determined by FT-IR, 1H NMR and LCMS. |
| |
| Keywords: | m-phenylenediamine m-acetamidoaniline acetaldehyde sodium triacetoxyborohyride m-(N,N -diethylamino)-acetanilide |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
