CHANGES OF CATHEPSIN D AND α _2- MACROGLOBULIN IN RATS AFTER ACUTE TOTAL BODY IRRADIATION |
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引用本文: | 金为翘,陈识杰,莫素珍,范佩芳,乐敏,张皓,李永河,何介薇.CHANGES OF CATHEPSIN D AND α _2- MACROGLOBULIN IN RATS AFTER ACUTE TOTAL BODY IRRADIATION[J].核技术(英文版),1990(3). |
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作者姓名: | 金为翘 陈识杰 莫素珍 范佩芳 乐敏 张皓 李永河 何介薇 |
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作者单位: | Institute of Radiation Medicine Shanghai Medical University Shanghai 200032 China,Institute of Radiation Medicine Shanghai Medical University Shanghai 200032 China,Institute of Radiation Medicine Shanghai Medical University Shanghai 200032 China,Institute of Radiation Medicine Shanghai Medical University Shanghai 200032 China,Institute of Radiation Medicine Shanghai Medical University Shanghai 200032 China,Institute of Radiation Medicine Shanghai Medical University Shanghai 200032 China,Institute of Radiation Medicine Shanghai Medical University Shanghai 200032 China,Institute of Radiation Medicine Shanghai Medical University Shanghai 200032 China |
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基金项目: | The Project Supported by National Natural Science Foundation of China |
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摘 要: | α 2-macroglobulin (α2M) could stimulate the regeneration of thymic and bone marrow cells in rats received γ-irradiation, but there was very few reports concerning its mechanism. Wistar rats were irradiated by 16Co at 7 Gy, 8.5 Gy, 15 Gy total body doses. Blood plasma and some tissue's extracts were collected α 2M level. a M activity and cathepsin D activity, malonaldehyde level were determined by radioimmunoassay, modified Schidlow's method, Barrett's method and Ohkawa's method respectively.
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