Characterization of chitosan/citrate and chitosan/acetate films and applications for wound healing |
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| Authors: | Junichi Tanigawa Norio Miyoshi Kensuke Sakurai |
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| Affiliation: | 1. Department of Materials Science and Engineering, Graduate School of Engineering, University of Fukui, Fukui 910‐8507, Japan;2. Department of Pathological Sciences, Faculty of Medicine, University of Fukui, Matsuoka, Yoshida‐Gun, Fukui 910‐1193, Japan |
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| Abstract: | In this work, we aimed to develop a scaffold of chitosan (CS) with a porous sponge structure for an artificial skin. The scaffolds were prepared from both CS/citric and CS/acetic solutions. In addition, the cast films were also prepared from the same solutions to compare some of their properties. They were characterized using WAXD, FTIR, DSC, tensile measurements, and SEM observation. It was found that CS/acetate had low crystallinity but CS/citrate was in an amorphous state, resulting in a large ductility with rubbery softness. Despite the different morphologies of CS/citrate and CS/acetate scaffolds, both scaffolds exhibited the wound healing effect available for tissue engineering. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008 |
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| Keywords: | scaffold chitosan wound healing microstructure |
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