| Abstract: | In this study, rose petal was used to fabricate osteon-like scaffolds for bone tissue engineering applications. Rose petal was coupled with nanocrystalline forsterite colloid to mimic the lamellar structure of porous osteons. The microstructures on the surface of the petals were utilized as template for pores and lacuna spaces which are suitable for cell attachment. On the other hand, rolling the petals allowed us to form the osteon structure with haversian canal and lacuna spaces on the body of the samples. After trying different temperatures, the results showed that samples annealed at 1100 °C closely mimicked the lacuna spaces, haversian canal, and lamellar structures of osteons. These scaffolds had the pore diameter in the range of about 13–20 μm and presented good bioactivity and biocompatibility. It was found that red rose petal is a good candidate to be used as a template for designing scaffolds for bone tissue engineering applications. |
