| 乙二胺为原料合成哌嗪及其衍生物的研究进展 |
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| 引用本文： | 李瑜,魏文珑,常宏宏,王志忠.乙二胺为原料合成哌嗪及其衍生物的研究进展[J].山西化工,2008,28(1):21-24. |
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| 作者姓名： | 李瑜 魏文珑 常宏宏 王志忠 |
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| 作者单位： | 太原理工大学化学化工学院,山西,太原,030024 |
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| 摘 要： | 介绍了以乙二胺为原料合成哌嗪及其衍生物的工艺方法.乙二胺可分别与环氧乙烷、乙二醇、一乙醇胺、二乙烯三胺等原料经不同的合成路线环合成哌嗪,也可自身环化合生成哌嗪.以乙二胺及其衍生物为初始原料,与其他有机物经过一系列的合成反应,可以生成哌嗪的衍生物.
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| 关 键 词： | 乙二胺 哌嗪 衍生物 合成 乙二胺 原料合成 哌嗪 衍生物 研究进展 ethylenediamine derivatives piperazine cyclization developments 合成反应 有机物 化合 环合成 合成路线 二乙烯三胺 一乙醇胺 乙二醇 环氧乙烷 可分 |
| 文章编号： | 1004-7050（2008）01-0021-04 |
| 收稿时间： | 2007-12-11 |
| 修稿时间： | 2007年12月11 |
Study developments on cyclization of piperazine and its derivatives from ethylenediamine |
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| LI Yu,WEI Wen-long,CHANG Hong-hong,WANG Zhi-zhong.Study developments on cyclization of piperazine and its derivatives from ethylenediamine[J].Shanxi Chemical Industry,2008,28(1):21-24. |
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| Authors: | LI Yu WEI Wen-long CHANG Hong-hong WANG Zhi-zhong |
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| Abstract: | This paper presents the process in which piperazine or its derivatives are synthesized by using ethylenediamine or its derivatives. Combined with ethylene oxide, ethylene glycol, monoethand-amine, and diethylenetriamine, respectively. Ethylenediamine can be used to synthesize piperazine in different routines, and ethylenediamine itself may cyclizate into piperazine. In addition, ethylenediamine or its diveratives, used as original reactions with other substances, can be used to produce the derivatives of piperazine through ethylenediamine series of synthesis reactions. Piperazine and its derivatives are important fine chemical materials and intermediates of medicines, and they have wide application. |
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| Keywords: | ethylenediamine piperazine derivative cyclization |
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