NF00659A1, A2, A3, B1 and B2, novel antitumor antibiotics produced by Aspergillus sp. NF 00659. II. Structural elucidation |
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| Authors: | K Suzuki A Kuwahara T Nishikiori T Nakagawa |
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| Affiliation: | Applied Microbiology Research Center, Nippon Kayaku Co., Ltd., Saitama, Japan. |
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| Abstract: | NF00659A1, A2, A3, B1 and B2, having insecticidal and antitumor activities, were isolated from a culture mycelium of Aspergillus sp. NF 00659. The novel structure of NF00659s were determined mainly by spectroscopic studies including various NMR measurements. NF00659s have a common structure which consists of acyl, alpha-pyrone and 4,5-seco-tricyclic diterpene moieties. |
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