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C5a Activates a Pro-Inflammatory Gene Expression Profile in Human Gaucher iPSC-Derived Macrophages |
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| Authors: | Jacquelyn C Serfecz Afsoon Saadin Clayton P Santiago Yuji Zhang Sren M Bentzen Stefanie N Vogel Ricardo A Feldman |
| Affiliation: | 1.Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA; (J.C.S.); (A.S.); (S.N.V.);2.The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;3.Department of Epidemiology and Public Health, University of Maryland, Baltimore, MD 21201, USA; (Y.Z.); (S.M.B.) |
| Abstract: | |
| Keywords: | gaucher disease induced pluripotent stem cells (iPSC) macrophages complement C5a inflammation TNF-alpha gene arrays GBA1 β -glucocerebrosidase |