尿激酶静脉溶栓治疗急性脑梗死临床分析

目的 观察静脉注射尿激酶溶栓治疗急性脑梗死的临床疗效及安全性。方法 采用静脉注射国产尿激酶(天普洛欣) 200 万U/人次, 治疗急性脑梗死28例, 以同期住院的30 例常规治疗病人作为对照。结果 溶栓组28 例中24 h内基本痊愈4 例, 显效8例, 而对照组无1 例有效。治疗后14 d溶栓组基本痊愈12 例, 显效6 例, 对照组基本痊愈1 例, 显效3例。溶栓组不同时间的显效率均比对照组高, 有显著性差异(P<0.05)。结论 静脉注射尿激酶治疗超早期脑梗死疗效明显。

Clinical analysis of intravenous infusion of fibrinolytic agent in the treatment of acute cerebral infarction

Aim To evaluate the clinical efficacy and safety of thrombolytic therapy for acute cerebral infarction. Methods Twenty-eig ht patients with acute cerebral infarction in the thrombotytic group were given an intravenous infusion of urokinase at the dose of 2 000 000 U and 30 patients received conventional therapy in the control group.Results Of the 28 cases, 4 recovered and 8 were markedly effective within 24 hours, while none of the 30 patients was effective. After 14 days, 12 patients in the thromboly tic group and one in the convent ional therapy group cured.The effective rate in the thromblytic group was higher than that in the conventional therapy group.Statist ical dif ference was found between the two groups. Conclusion Early int ravenous thromboly tic therapy with urokinase shows remarkable efficacy for acute cerebral infarction.