| 血液灌流抢救超大剂量地高辛中毒 |
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| 引用本文： | 杨红军,原新茹,张锡刚,牛文凯.血液灌流抢救超大剂量地高辛中毒[J].金属学报,2002,7(4):337-338. |
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| 作者姓名： | 杨红军 原新茹 张锡刚 牛文凯 |
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| 作者单位： | 军事医学科学院附属医院血透室, 北京 100039 |
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| 摘 要： | 目的: 观察1例血液灌流抢救超大剂量( 50mg)地高辛中毒的效果。方法: 使用HA 330 ml 灌流器和YT-160 灌流器, 血管通路为股静脉单针双腔导管。入院后共进行了4 次血液灌流( HP) 治疗。结果: 第1 次HP 前后检测地高辛血药浓度均16 μg·L-1。第2 次HP 血药浓度9. 22 μg·L-1。第3 次HP 前血药浓度12. 4 μg·L-1, HP 后为10. 45 μg·L-1。第4 次HP 前3. 22 μg·L-1, HP 后为2. 84 μg·L-1。结论: 采用间隔一定的时间HP, 多次进行, 可阶梯式降低药物浓度。
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| 关 键 词： | 地高辛 血液灌流 中毒 |
| 收稿时间： | 2001-12-27 |
| 修稿时间： | 2002-03-20 |
Hemoperfusion in treatment of overdose digoxin poisoning |
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| YANG Hong-Jun,YUAN Xin-Ru,ZHANG Xi-Gang,NIU WEN-Kai.Hemoperfusion in treatment of overdose digoxin poisoning[J].Acta Metallurgica Sinica,2002,7(4):337-338. |
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| Authors: | YANG Hong-Jun YUAN Xin-Ru ZHANG Xi-Gang NIU WEN-Kai |
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| Affiliation: | Affiliated Hospital to Academy of Military Medical Sciences, Beijing 100039 |
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| Abstract: | AIM: To observe the efficacy of hemoperfusion ( HP) to treat one case suffering from overdose digoxin poisoning. METHODS: HA 330 ml and YT-160 hemoperfusion cartridges were used and blood vessel was femoral vein, single needle and two-chamber catheter. Four HP were done. RESULTS: The blood digoxin level were 16 μg·L-1 before and after the 1st HP, 9. 22 μg· L-1 at the 2nd, 12. 4 μg·L-1 before the 3th, 10. 45 μg· L-1after the 3th, 3. 22 μg ·L -1before the 4th, and 2. 84 μg·L-1 after the 4th HP. CONCLUSION: This case demonstrats that multiple HP at different period may decrease the blood digoxin level step by step. |
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| Keywords: | digoxin hemoperfusion poisoning |
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