A New Formulation Based on Ozonated Sunflower Seed Oil: In Vitro Antibacterial and Safety Evaluation |
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| Authors: | Francesca Serio Graziano Pizzolante Giuseppe Cozzolino Maria D’Alba Francesco Bagordo Mattia De Giorgi |
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| Affiliation: | 1. Department of Biological and Environmental Science and Technology, University of the Salento, 73100 Lecce, Italy!["ORCID]("/templates/jsp/images/orcid.png" "\"ORCID") http://orcid.org/0000-0002-2782-2798;2. Department of Biological and Environmental Science and Technology, University of the Salento, 73100 Lecce, Italy;3. Department of Vascular and Endovascular Surgery, Hospital “Cardinal G. Panico”, 73039 Tricase, Italy;4. Department of Nephrology and Dialysis, Hospital “V. Delli Ponti”, 73020 Scorrano, Italy;5. Department of Biological and Environmental Science and Technology, University of the Salento, 73100 Lecce, Italyhttp://orcid.org/0000-0001-5208-5382 |
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| Abstract: | The objective of this study was to investigate the potential in vitro biological properties of Oz.Or.Oil 30, a new formulation composed of 30% ozonated sunflower seed oil, which is believed to keep skin smooth and moisturized, supporting repair processes, tissue regeneration and re-epithelialization of wounds. The antibacterial activity, the qualitative and quantitative evaluation of the cytotoxic effect of the formulation on cultures of Vero cells and 3T3 fibroblasts showed that Oz.Or.Oil 30 merits further in vivo study using clinical-laboratory correlations, because it could be suggested as an alternative therapy against bacterial and fungal diseases. |
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| Keywords: | Ozone Antibacterial Activity Cytotoxicity Dermatological Gel Ozonated Sunflower Seed Oil Preservative Efficiency |
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