Porous calcium phosphate ceramics prepared by coating polyurethane foams with calcium phosphate cements |
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| Affiliation: | 1. Department of Chemistry, National Chung Hsing University, Taichung, 402, Taiwan;2. Department of Chemistry, Chung Yuan Christian University, Chung-Li, 32023, Taiwan;3. Technology Research Development, Plastic Industrial Development Center, Taichung, 407, Taiwan;1. Faculty of Chemical and Petroleum Engineering, University of Tabriz, 51666-16471, Tabriz, Iran;2. Department of Basic Sciences, Farhangian University, Tehran, Iran;1. Institute of Materials Science of Barcelona (ICMAB-CSIC), Campus de la UAB, Bellaterra, 08193, Spain;2. Centre for Advanced Biomaterials for Health Care, Istituto Italiano di Tecnologia, Largo Barsanti e Matteucci 53, 80125 Napoli, Italy;1. Institute of Advanced Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia;2. Department of Physics, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia;3. Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia |
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| Abstract: | Porous calcium phosphates have important biomedical applications such as bone defect fillers, tissue engineering scaffolds and drug delivery systems. While a number of methods to produce the porous calcium phosphate ceramics have been reported, this study aimed to develop a new fabrication method. The new method involved the use of polyurethane foams to produce highly porous calcium phosphate cements (CPCs). By firing the porous CPCs at 1200 °C, the polyurethane foams were burnt off and the CPCs prepared at room temperature were converted into sintered porous hydroxyapatite (HA)-based calcium phosphate ceramics. The sintered porous calcium phosphate ceramics could then be coated with a layer of the CPC at room temperature, resulting in high porosity, high pore interconnectivity and controlled pore size. |
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