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Mild and Direct Multiple Deuterium‐Labeling of Saturated Fatty Acids |
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| Authors: | Tsuyoshi Yamada Kwihwan Park Naoki Yasukawa Kosuke Morita Yasunari Monguchi Yoshinari Sawama Hironao Sajiki |
| Abstract: | We have established a mild and direct platinum on carbon (Pt/C)‐catalyzed multi‐deuterium labeling of various saturated fatty acids including bioactive compounds with high deuterium efficiencies in a mixed solvent of isopropyl alcohol and deuterium oxide (i‐PrOH)/D2O under neutral conditions at 120 °C without the external addition of deuterium or hydrogen gas.  |
| Keywords: | deuterium fatty acids isopropyl alcohol platinum on carbon valproic acid |