Affiliation: | 1. Department of Mechanical Engineering, National Taiwan University, Taipei, Taiwan
School of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan;2. Institute of Physics, Academia Sinica, Nankang, Taipei, Taiwan;3. School of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan;4. Department of Materials Science and Engineering, Feng Chia University, Taichung, Taiwan;5. Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan;6. Department of Mechanical Engineering, National Taiwan University, Taipei, Taiwan |
Abstract: | Due to its excellent bioactivity, bioactive glass (BG) is suitable for use as bone graft substitutes in biomedical applications. In this study, carbon nanotubes (CNT-COOH) served as templates for depositing bioactive glass based on 60SiO2–36CaO–4P2O5 wt.% were synthesized via the solgel process. The BG and BG/CNT-COOH composites were treated at 300, 500, 700, and 900°C; their properties were also examined by X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy. The experimental results showed that BG/CNT-COOH composites treated at 500 and 700°C were amorphous and contained silicate nanocrystals. By altering precursor concentration, bioactive glass of various thicknesses was successfully solgel coated on CNT-COOH. Immersion of the BG/CNT-COOH composites in simulated body fluid solution and MG-63 cell culture assessment showed the 500°C treated BG/CNT-COOH exhibits excellent bioactivity. |