Voices of fear and anxiety and sadness and depression: The effects of speech rate and loudness on fear and anxiety and sadness and depression.

Two studies investigated the role of expressive vocal behavior (specifically, speech rate and loudness) in fear and anxiety and in sadness and depression. In the 1st study, participants spoke about personally experienced fear and anxiety-arousing and neutral events using 3 different voice styles: fast and loud, normal, and slow and soft. In the 2nd study, participants spoke about personally experienced sad or depressing and neutral events using the same 3 voice styles. In both studies, the participants' highest levels of subjective affective and cardiovascular (CV) arousal occurred when they spoke about the emotional events in a mood-congruent voice style: fast and loud in the case of fear and anxiety, and slow and soft in the case of sadness or depression. Mood-incongruent voice styles canceled the heightened levels of CV arousal normally associated with these negative emotions. The voice-style manipulation had no significant effect on the participants' levels of CV arousal during the neutral discussions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Spondylolysis and spondylolisthesis and sports

Spondylolysis and spondylolisthesis occur predominantly in the lower lumbar spine. Besides congenital defects such as predisposition of spondylolysis the correlation between competitive sports activities and an increased incidence of spondylolysis is proved. In early stages, complete healing can be achieved by conservative treatment (abstinence from sports activities for 3 months, orthesis). Persistence of pain, neurologic symptoms and progression of vertebral slipping are indications for operative treatment (reconstruction of the isthmus, dorso-ventral spondylodesis). The exercise tolerance depends on the extent of instability, progression of vertebral slipping and clinical symptoms. The limits of exercise tolerance vary among the individual athletes and require the decision of the physician. Backstroke swimming, abdominal and back muscle strengthening exercises, and types of sport involving smooth movements are advisable. Sports education in school is possible without restriction in patients with stable spondylolysis and in those with spondylolisthesis without unfavourable concomitant factors.     

Synthesis and analysis of mixed chlorinated-fluorinated dibenzo-p-dioxins and dibenzofurans and assessment of formation and occurrence of the fluorinated and chlorinated-fluorinated dibenzo-p-dioxins and dibenzofurans

Despite the use of multimodal therapy, higher-grade glioma is still uniformly fatal in the adult population. There is a considerable difference between the length of survival in each given patient, even within the same tumor type and malignancy grade group, suggesting that there are factors that might differentially influence outcome. To identify such factors, 107 patients with anaplastic or malignant glioma were retrospectively investigated. Clinical parameters and paraclinical data on the p53, mdm2, and EGFR genes at the DNA or protein level were evaluated by univariate analysis and Cox proportional hazards regression modeling. Kaplan-Meier survival estimation demonstrated that immunohistochemical positivity for mdm2 protein in patients with anaplastic astrocytoma or with glioblastoma multiforme was associated with a shorter survival time (p = 0.02). P53 gene mutations and immunopositivity for the epidermal growth factor receptor (EGFR) protein were not significantly related to poor prognosis. The Cox proportional hazards model revealed immunohistochemical positivity for p53, mdm2, or for both of them, the presence of postoperative irradiation, and the extent of surgical resection of tumor to be variables significantly associated with prolonged survival. EGFR overexpression, age over 60 years, and Karnofsky performance score below 40 points did not significantly shorten survival time. In conclusion, the present study identified immunohistochemically detected mdm2-protein overexpression as a statistically significant negative prognostic parameter in patients bearing anaplastic or malignant glioma. Association analysis of variables revealed a possible correlation between mdm2 and p53, which is also consistent with the biological interaction mode of both proteins in vivo.     

Sexuality and aging--usual and successful

BACKGROUND: As aging research increasingly reflects an effort to dissociate true time-driven changes from those that can be improved, sexuality in later life remains largely unexplored. Several problems are evident. There is a lack of normative data, a lack of a conceptual framework relating to the biology, psychology, and sociology of sex, and an attitudinal resistance that obscures the entire topic. METHODS: We conducted a three-part instructional series on major topics involved with sexuality and aging. We surveyed our group of attendees (n 158, average age 68 for males, 65 for females) before and after the series. RESULTS: A remarkably robust sex life was evidenced by both the men and the women, even until advanced old age. Yet, a substantially decreased involvement was reported from 10 years earlier. Despite current activities, people of both sexes wished they were participating even more than they currently were. Impotency was identified as the major negative feature for the men; relationship problems were for the women. A questionnaire 6 months after the series reported improved sexual attitudes, but no change in sexual activities from the earlier survey. CONCLUSION: Sexuality is a major quality-of-life issue which persists into old age. Our study showed that the usual sexual practices reported by our group were not considered by them to be ideal. The intervention of this instructional series provided improved sexual attitudes but not performance. Additional studies are encouraged.     

Larks and owls and health, wealth, and wisdom

OBJECTIVE: To test the validity of Benjamin Franklin's maxim "early to bed and early to rise makes a man healthy, wealthy, and wise." DESIGN: Cross sectional analysis of sleeping patterns in a nationally representative group of elderly people, and longitudinal investigation of mortality. SETTING: Eight areas in Britain (five in England, two in Scotland, and one in Wales). SUBJECTS: 1229 men and women aged 65 and over who in 1973-4 had taken part in a survey funded by the Department of Health and Social Security and for whom data on sleeping patterns, health, socioeconomic circumstances, and cognitive function had been recorded. MAIN OUTCOME MEASURES: Self reported income, access to a car, standard of accommodation, performance on a test of cognitive function, state of health and mortality during 23 years of follow up. RESULTS: 356 people (29%) were defined as larks (to bed before 11 pm and up before 8 am) and 318 (26%) were defined as owls (to bed at or after 11 pm and up at or after 8 am). There was no indication that larks were richer than those with other sleeping patterns. On the contrary, owls had the largest mean income and were more likely to have access to a car. There was also no evidence that larks were superior to those with other sleeping patterns with regard to their cognitive performance or their state of health. Both larks and owls had a slightly reduced risk of death compared with the rest of the study sample, but this was accounted for by the fact that they spent less time in bed at night. In the study sample as a whole, longer periods of time in bed were associated with increased mortality. After adjustment for age, sex, the presence of illness, and other risk factors, people who spent 12 or more hours in bed had a relative risk of death of 1.7 (1.2 to 2.5) compared with those who were in bed for 9 hours. The lowest risk occurred in people who spent 8 hours in bed (adjusted relative risk 0.8; 0.7 to 1.0). CONCLUSION: These findings do not support Franklin's claim. A "late to bed and late to rise" lifestyle does not seem to lead to socioeconomic, cognitive, or health disadvantage, but a longer time spent in bed may be associated with increased mortality.     

材料科学技术转型发展与钢铁创新基础设施的建设

摘要：在第4次工业革命浪潮的推动下,钢铁科学与技术正在经历数字化、智能化转型。钢铁行业全流程各工序均为“黑箱”,为多场、多相、多变的巨系统,具有复杂相关关系和遗传效应等。这些不确定性带来了巨大的挑战。挑战和机遇并存。这些不确定性提供了智能化和数字化技术的应用场景资源;钢铁行业极为丰富的大数据提供了挖掘其中蕴含客观规律的数据资源;现代的数据科学、智能技术为解决不确定性问题提供了强大的手段。以数据为中心,以工业互联网为载体,以实验工具、数字数据、计算工具为支撑,建设钢铁企业材料创新基础设施,将可以大幅度提高研发效率,降低研发成本,有力地支撑钢铁材料科学与技术的转型发展。实验工具平台除了传统的实验室仪器装备和中试装备之外,实际生产线被作为主要的实验工具。这些实验工具提供丰富、精准、写实的历史数据和现实生产数据,特别是生产线装备提供实际生产大数据,蕴含着生产过程中的全部规律,是极宝贵的数据资源。利用机器学习、深度学习等现代数据挖掘技术为计算工具,对这些数据资源进行处理、分析、计算,将数据转换为高保真度模型,可以得到具有“原位分析能力”的数字孪生。在工业互联网的总体架构下,以数字孪生为核心,组成信息物理系统,构建起基于数据自动流动的状态感知、实时分析、科学决策、精准执行的闭环赋能体系,解决生产制造、应用服务过程中的复杂性和不确定性问题,提高资源配置效率,实现资源优化,对材料行业转型发展提供关键技术支撑。虚实映射、实时交互、精准控制的信息物理系统与材料创新基础设施合二为一,以材料创新基础设施为基盘,形成具有“原位分析能力”的数字孪生,建设钢铁生产全流程、一体化的信息物理系统,必将推进钢铁行业智能制造蓬勃开展和数字化、智能化转型。     

Daydreaming and curiosity in gifted and average children and adolescents.

307 gifted (CA 10–16 yrs; mean IQ 138.8) and 192 age-matched average Ss (IQ 100.8) completed the Imaginal Processes Inventory, the Children's Reactive Curiosity Scale, and the Academic Curiosity Scale. Demographic and IQ data were obtained from Ss' school records. Factor analysis of the data resulted in factors indicative of individual difference dimensions in daydreaming content and curiosity independent of demographic and IQ factors. Analyses of factor scores by grade level revealed decreasing linear trends over grade on the Guilt and Fear of Failure Daydreaming factor in both groups. Increasing trends over grade level were found for the Curiosity and Positive-Constructive Daydreaming factors in the gifted group. Average Ss showed a developmental decline in curiosity. Compared to average Ss, gifted Ss had higher Curiosity factor scores, lower Guilt and Fear of Failure Daydreaming scores, and higher scores on the Intelligence and Family Enrichment factor. The validity of the distinction between intellectual power and intellectual styles and the development of intellectual styles are discussed. (17 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Praise and Blame and Robinson.

Daniel Robinson suggests that much of the civil and criminal law "serves as the institutionalized form of praise and blame". Indeed it does. Pulling at this thread of Robinson's tapestry leads the reader straightaway to a host of truths about how law and morality not only intersect, but work together in harmony. "[L]aw", Robinson says, is a "vivid expression of deeper and impenetrably complex moral theories". This essay explores several of these harmonies, but focuses on two. One is that political society must be seen as the cooperation of free persons according to law, which persons hold common moral understandings. The second has to do with retribution as the moral justifying aim of punishing criminals. The author goes beyond Robinson's limited praise of retribution, and shows that some central features of our practice of punishment are understandable only within the retributive framework. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

IQ and ego-resiliency: Conceptual and empirical connections and separateness.

The constructs of intelligence and ego-resiliency are discussed. The personality implications of "pure intelligence" and "pure ego-resilience" were identified. Intelligence (IQ) was indexed by the Wechsler Adult Intelligence Scale-Revised (WAIS—R) and ego-resiliency by an inventory scale. Residual scores measuring "pure intelligence" and "pure ego-resilience" were correlated with the items of the observer based California Q-sort, used to describe participants. Persons relatively high on ego-resilience tend to be more competent and comfortable in the "fuzzier" interpersonal world; persons defined primarily by raw IQ tend to be effective in the "clearer" world of structured work but tend also to be uneasy with affect and less able to realize satisfying human connections. Gender differences exist in the relations of ego-resilience and intelligence and in their adaptive relevance. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Conserving and retaining equalities and inequalities through observation and correction.

Investigated the effects of modeling and corrective feedback on the conservation of equalities and inequalities, with items spanning 3 stimulus dimensions (length, number, and 2-dimensional space). Ss were 48 kindergartners (24 boys, 24 girls). Brief observation of a model, briefer correction training (joining positive feedback with verbal rule provision), and the combination of observation and correction were all successful in producing learning and, without further training, transfer and retention of conservation. Unlike the controls (who also never correctly answered any equality items), the trained experimental Ss gave evidence of spontaneously generalizing their new learning to a task that required nonverbal behavior to manifest conservation. (17 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

深云立交桥梁检测及加固改造

根据深云立交桥梁的检测结果，对该桥目前的整体状况、工作状态，及其使用情况做出综合评价，对桥的病害原因进行了分析，并提出合理的加固方案。     

关于摩尔浓度及其与硬度转换关系问题的讨论

众所周知，国际单位制物质的量采用摩尔(mol)表示，近几年出版的给排水专业书籍，为了与国际单位制接轨，逐渐将摩尔的使用频率不断提高，被给排水技术人员广泛应用的新版给排水设计手册，将表示物质浓度的单位“当量／升”或“毫克当量／升”．改为mol／l或mmol／l，虽然编者对其基本单元定义作了说明，但在实际运用上仍会出现误解，     

抗腐蚀高强耐磨涂料研发与应用

介绍了抗腐蚀高强度耐磨涂料的研制和开发，以及用作柳钢球团回转烘干机刮板保护涂层的应用效果。     

《儿子与情人》的语码转换与男女二元对立

劳伦斯小说《儿子与情人》一个鲜明的语言特色就是标准英语和当地方言频繁的语码转换。莫瑞尔用方言来对抗妻子,而妻子坚持用标准英语,偶尔也用方言来讽刺、挖苦丈夫。语码转换反映了劳伦斯男女二元对立的哲学思想。     

Reasoning and food and contamination.

Examines strategies that are used to reason about food and contamination. In Exp 1, Ss refrained from choosing a substance that had been given a "poison" label when the intent of the labeler was ambiguous or malicious but preferred this substance when a rationale was provided that dispelled the implication that there once might have been contaminants present. Exp 2 was designed to compare the effects of safety on conditional reasoning in food and food-irrelevant contexts. When the safety issue was relevant to food in the form of contamination, Ss were most likely to use formal logic in reasoning. A similar pattern of responses was found in Exp 3 on tasks for which Ss' ratings of their experience of contexts were matched for plausibility, experience, and danger. Results are discussed in terms of an adaptive constraint that facilitates rationality in reasoning within the food domain (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Prohormone and proneuropeptide synthesis and secretion

Hormones and neuropeptides in eukaryotic cells, are synthesised as large precursor molecules in the rough endoplasmic reticulum (RER), from where they are translocated to the Golgi apparatus. The sorting of proteins destined for the regulated secretory pathway from those which will be released constitutively takes place in the trans-Golgi network (TGN). In both these pathways, vesicles need to be transported to the plasma membrane before their contents can be released by exocytosis. Hormones and neuropeptides need to be secreted from the cells in which are synthesised to exert their biological actions, although they can also play paracrine and autocrine actions. Prohormones and proneuropeptides must undergo post-translational modifications which occur in determined subcellular compartments within eukaryotic cells and are carried out in a strict succession of intracellular events, which give rise to biologically active products. The biosynthesis of prohormones/proneuropeptides is mediated by the action of endoproteolytic enzymes and other post-translational modifying enzymes within the secretory pathway. The major focus of this review will be the biosynthetic pathway, sorting and intracellular trafficking of prohormone and proneuropeptide precursors within the secretory pathway of eukaryotic cells.     

Comment on Mazza and Stevens and on Miller and Hester.

Supplements D. Mazza and D. Stevens's (1988) critique of W. R. Miller and R. K. Hester's (see record 1986-28253-001) review of alcoholism treatment. Of 6 studies cited in the review, 2 did not compare inpatient and outpatient treatment; 4 were conducted over 13 yrs earlier; methodological limitations of the studies preclude conclusions about outcomes; and the studies focused on late-stage, chronic populations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Screening and treatment of children and adolescents with hypercholesterolemias and dyslipidemias

Evidence was provided that atherogenesis develops for several decades before pathological changes are manifested. It may thus be stated, that the "incubation period" of atherosclerotic pathological consequences is very long but it is reduced markedly already from childhood and adolescence in subjects with an atherogenic lipoprotein phenotype. Atherogenic lipoprotein phenotype comprises subjects suffering from one or more, frequently from a combination of several of the following metabolic indicators: hypercholesterolaemia, elevated levels of LDL-cholesterol, apolipoprotein B, lipoprotein (a), reduced levels of HDL-cholesterol and apolipoprotein A-1. The atherogenic lipoprotein phenotype is in 95% conditioned by inborn metabolic errors, i.e. familial hyperlipoproteinaemia and dyslipoproteinaemia. In the population the following are encountered most frequently: combined familial hyperlipidaemia, familial hypertriacylglycerolaemia and familial hypercholesterolaemia. Active screening and treatment of children and adolescents from these affected families is of great importance in primary prevention of atherosclerotic complications in adult age.     

Words and things and images.

Explores and evaluates the current renaissance of interest in imagery as a cognitive mechanism, with reference to its role in associative learning, mediation, meaning, and personality. The variable of time is stressed in the formation of effective imagery in mnemonic research. Experiments are described in which Ss, instructed to image but not to learn, were unable to prevent learning. Imagery is relatively free from interference in memorizing successive lists, and highly effective in recall of long lists of concrete and abstract words. Abstract words are frequently transposed into concrete representations. Research employing 3-6 yr. old deaf children without language of any known variety supports assumptions about imagery. (30 ref.) (PsycINFO Database Record (c) 2010 APA, all rights reserved)