全文获取类型
收费全文 | 7851篇 |
免费 | 542篇 |
国内免费 | 284篇 |
专业分类
电工技术 | 258篇 |
综合类 | 574篇 |
化学工业 | 1477篇 |
金属工艺 | 166篇 |
机械仪表 | 393篇 |
建筑科学 | 568篇 |
矿业工程 | 451篇 |
能源动力 | 174篇 |
轻工业 | 2025篇 |
水利工程 | 419篇 |
石油天然气 | 216篇 |
武器工业 | 20篇 |
无线电 | 226篇 |
一般工业技术 | 301篇 |
冶金工业 | 413篇 |
原子能技术 | 91篇 |
自动化技术 | 905篇 |
出版年
2024年 | 28篇 |
2023年 | 105篇 |
2022年 | 316篇 |
2021年 | 346篇 |
2020年 | 229篇 |
2019年 | 164篇 |
2018年 | 188篇 |
2017年 | 205篇 |
2016年 | 245篇 |
2015年 | 245篇 |
2014年 | 367篇 |
2013年 | 437篇 |
2012年 | 493篇 |
2011年 | 517篇 |
2010年 | 404篇 |
2009年 | 429篇 |
2008年 | 381篇 |
2007年 | 479篇 |
2006年 | 430篇 |
2005年 | 379篇 |
2004年 | 340篇 |
2003年 | 328篇 |
2002年 | 282篇 |
2001年 | 232篇 |
2000年 | 162篇 |
1999年 | 177篇 |
1998年 | 111篇 |
1997年 | 116篇 |
1996年 | 98篇 |
1995年 | 58篇 |
1994年 | 73篇 |
1993年 | 55篇 |
1992年 | 46篇 |
1991年 | 39篇 |
1990年 | 35篇 |
1989年 | 18篇 |
1988年 | 22篇 |
1987年 | 19篇 |
1986年 | 10篇 |
1985年 | 15篇 |
1984年 | 12篇 |
1983年 | 12篇 |
1982年 | 6篇 |
1981年 | 3篇 |
1980年 | 5篇 |
1977年 | 2篇 |
1975年 | 2篇 |
1974年 | 3篇 |
1964年 | 2篇 |
1959年 | 2篇 |
排序方式: 共有8677条查询结果,搜索用时 15 毫秒
1.
2.
为研究金针菇多糖(polysaccharide from Flammulina velutipes,FVP)对微冻大黄鱼及鱼片在贮藏期间肌原纤维蛋白性质的变化及水分分布的影响,实验分别选用0.03、0.06、0.09 g/L FVP浸渍处理大黄鱼和鱼片,以无菌水处理为对照组,分析微冻贮藏期间样品的感官指标得分、总挥发性盐基氮含量、总巯基含量、Ca2+-ATPase活性、蛋白流变学性质以及水分迁移变化规律。结果表明:FVP可有效抑制整鱼总挥发性盐基氮含量上升和感官得分的下降;减缓整鱼及鱼片在微冻过程中总巯基含量、Ca2+-ATPase活性下降和水分流失;此外FVP还能够延缓大黄鱼因腐败而出现的蛋白凝胶能力减弱。在本实验选取的多糖浓度范围内,0.09 g/L FVP处理组保鲜效果较强。该研究结果可为FVP用于水产品贮运保鲜提供理论参考。 相似文献
3.
Ionela-Dorina Dumbrava Calin-Cristian Cormos 《International Journal of Hydrogen Energy》2021,46(45):23149-23163
Hydrogen production by biogas conversion represent a promising solution for reduction of fossil CO2 emissions. In this work, a detailed techno-economic analysis was performed for decarbonized hydrogen production based on biogas conversion using calcium and chemical looping cycles. All evaluated concepts generate 100,000 Nm3/h high purity hydrogen. As reference cases, the biogas steam reforming design without decarbonization and with CO2 capture by gas-liquid chemical absorption were also considered. The results show that iron-based chemical looping design has higher energy efficiency compared with the gas-liquid absorption case by 2.3 net percentage points as well as a superior carbon capture rate (99% vs. 65%). The calcium looping case shows a lower efficiency than chemical scrubbing, with about 2.5 net percentage points, but the carbon capture rate is higher (95% vs. 65%). The hydrogen production cost increases with decarbonization, the calcium looping shows the most favourable situation (37.14 €/MWh) compared to the non-capture steam reforming case (33 €/MWh) and MDEA and iron looping cases (about 42 €/MWh). The calcium looping case has the lowest CO2 avoidance cost (10 €/t) followed by iron looping (20 €/t) and MDEA (31 €/t) cases. 相似文献
4.
5.
Deunsol Hwang Jong-Beom Seo Hun-Young Park Jisu Kim Kiwon Lim 《International journal of molecular sciences》2021,22(2)
While exercise training (ET) is an efficient strategy to manage obesity, it is recommended with a dietary plan to maximize the antiobesity functions owing to a compensational increase in energy intake. Capsiate is a notable bioactive compound for managing obesity owing to its capacity to increase energy expenditure. We aimed to examine whether the antiobesity effects of ET can be further enhanced by capsiate intake (CI) and determine its effects on resting energy expenditure and metabolic molecules. Mice were randomly divided into four groups (n = 8 per group) and fed high-fat diet. Mild-intensity treadmill ET was conducted five times/week; capsiate (10 mg/kg) was orally administered daily. After 8 weeks, resting metabolic rate and metabolic molecules were analyzed. ET with CI additively reduced the abdominal fat rate by 18% and solely upregulated beta-3-adrenoceptors in adipose tissue (p = 0.013) but did not affect the metabolic molecules in skeletal muscles. Surprisingly, CI without ET significantly increased the abdominal fat rate (p = 0.001) and reduced energy expenditure by 9%. Therefore, capsiate could be a candidate compound for maximizing the antiobesity effects of ET by upregulating beta-3-adrenoceptors in adipose tissue, but CI without ET may not be beneficial in managing obesity. 相似文献
6.
Sophia X. Sui Lana J. Williams Kara L. Holloway-Kew Natalie K. Hyde Julie A. Pasco 《International journal of molecular sciences》2021,22(1)
Sarcopenia is the loss of skeletal muscle mass and function with advancing age. It involves both complex genetic and modifiable risk factors, such as lack of exercise, malnutrition and reduced neurological drive. Cognitive decline refers to diminished or impaired mental and/or intellectual functioning. Contracting skeletal muscle is a major source of neurotrophic factors, including brain-derived neurotrophic factor, which regulate synapses in the brain. Furthermore, skeletal muscle activity has important immune and redox effects that modify brain function and reduce muscle catabolism. The identification of common risk factors and underlying mechanisms for sarcopenia and cognition may allow the development of targeted interventions that slow or reverse sarcopenia and also certain forms of cognitive decline. However, the links between cognition and skeletal muscle have not been elucidated fully. This review provides a critical appraisal of the literature on the relationship between skeletal muscle health and cognition. The literature suggests that sarcopenia and cognitive decline share pathophysiological pathways. Ageing plays a role in both skeletal muscle deterioration and cognitive decline. Furthermore, lifestyle risk factors, such as physical inactivity, poor diet and smoking, are common to both disorders, so their potential role in the muscle–brain relationship warrants investigation. 相似文献
7.
Andrea Mariela Araya-Sibaja Valdir Soldi Carlos Eduardo Maduro Campos Simone Gonçalves Cardoso 《Drug development and industrial pharmacy》2015,41(5):851-858
Progesterone is a natural hormone steroid used in humans for several treatments and in livestock for artificial insemination, which exhibits two polymorphic forms at ambient conditions: form 1 and form 2. Form 2 is metastable and more soluble than form 1; however, it is not suitable to use as powder raw material because it transforms into form 1 by the effects of grinding. A polymorphic screening of progesterone based on polymer-induced heteronucleation method was performed as an alternative to prepare the metastable form. Polyvinyl alcohol, hydroxypropyl methylcellulose (HPMC), dextran, gelatin, polyisoprene (PI) and acrylonitrile-butadiene (NBR) copolymer were used. Crystals were prepared from 0.5, 10 and 40?mg/mL solutions in acetone at room temperature by solvent evaporation. The samples were characterized by X-ray powder diffraction, differential scanning calorimetry (DSC), scanning electron microcopy and attenuated total reflectance infrared Fourier transform spectroscopy. Form 1 was nucleated from 40?mg/mL solutions on the six polymers and from 10?mg/mL solutions on PI and NBR. The mixture of form 1 and form 2 was obtained from 10?mg/mL solution on HPMC, dextran and gelatin and from 0.5?mg/mL solution crystallizations. Therefore, the polymeric devices, which crystallized the metastable and more soluble polymorph (2) of progesterone, would be a promissory alternative for the pharmaceutical applications. 相似文献
8.
露天转地下联合开采技术探讨 总被引:3,自引:0,他引:3
针对复杂型锰矿开采提出了由露天转地下联合开采技术,与其它采矿方法相比较,这种方法提高了回采率,降低了采矿成本。 相似文献
9.
10.
S. MESCHINI A. MOLINARI A. CALCABRINI G. CITRO G. ARANCIA 《Journal of microscopy》1994,176(3):204-210
The intracellular distribution of the anthracyclinic antibiotic adriamycin in living cultured cells has been investigated by confocal microscopy. In human melanoma cells (M14), adriamycin was localized inside the nuclei. When adriamycin-treated M14 cells were allowed to recover in drug-free medium, a complete efflux of the drug from the nucleus was revealed. In recovered cells, a weakly fluorescent signal was observed in the perinuclear region. When M14 cells were recovered in a medium containing colcemid, a microtubule depolymerizing agent, the drug transport from the nucleus to the cell periphery appeared to be inhibited, suggesting that the microtubule network is strongly involved in drug transport mechanisms. In multidrug-resistant (MDR) cells the intracellular location of adriamycin was shown to be noticeably different from that of the parental wild-type cells. In particular, in resistant human breast carcinoma cells (MCF-7), adriamycin appeared to be exclusively located within the cytoplasm whereas the nuclei were shown to be completely negative. When adriamycin treatment was performed in association with MDR revertants, such as Lonidamine (inhibitor of the energy metabolism) or verapamil (inhibitor of the P-glycoprotein efflux pump), a marked enhancement of the cytoplasmic signal was observed in resistant cells. Under these conditions, adriamycin appeared concentrated in the perinuclear region, but the nuclei were still negative. Confocal microscopy proved to be a very useful method for the study of the intracellular transport of fluorescent substances, such as anthracyclinic antibiotics, and for the investigation of the multidrug resistance phenomenon in tumour cells. 相似文献