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51.
Obesity is now recognised as the most prevalent nutritional disorder affecting children. Prevalence rates across Europe have increased sharply in the past decade and the consequences of this are increasingly clear with type 2 diabetes, hyperlipidaemia and hypertension now affecting children in growing numbers. The causes of this modern epidemic are many and involve complex genetic and environmental factors and the traditional view of obesity as a product of laziness and greed is increasingly being challenged. Whatever the causes, prevention and treatment need to be considered with urgency. While personal and parental responsibility remain crucial, it also falls to government to help control powerful environmental pressures which are leading our children into premature ill‐health and mortality. Equally health professionals are increasingly recognising that they have a significant role to play in delivering medical treatment of obesity in children. Successful treatment requires a greater understanding of obesity, causes, and consequences, and of the particular style of approach that is required for children, and their families. The role of weight loss medication remains unclear, but is being examined seriously, such is the need for effective treatment strategies to minimise the incidence and severity of co‐morbid disease. Inaction at any level can no longer be considered a viable option.  相似文献   
52.
The cobalt(II) chloride-catalyzed oxidative cleavage of -methylstyrene with oxygen in t-BuOH gives acetophenone and formaldehyde in good yield. The competing reactions between C=C cleavage and formation of polymeric products are strongly affected by the solvent, cobalt catalyst and concentration used, as well as the reaction temperature. A free radical mechanism involving a cyclic peroxide intermediate is proposed to give the cleavage products. Oxidation of various alkenes using CoCl2/t-BuOH/O2 system shows that only activated styrenes can be oxidized effectively. The reactivity of various styrenes and their selectivity towards giving cleavage products or polymers are strongly influenced by the electronic and steric properties of the substrate.  相似文献   
53.
We examined the effects of inhibitors of the octadecanoid pathway (n-propyl gallate, acetosalicylic acid, salicylhydroxamic acid, methyl salicylate, and antipyrine) on wound- and jasmonate-induced nicotine accumulation and compared the nicotine-inducing ability of exogeneous additions of linolenic acid (18:3) and its methyl ester, linoleic acid (18:2), abscisic acid, traumatic acid, and methyl dihydrojasmonate to the nicotine-inducing ability of exogenous additions of methyl jasmonate (MJ). The first four of these inhibitors significantly reduced wound-induced nicotine accumulation when applied in a lanolin paste to wounded tissues immediately after wounding at concentrations of 89–90µg/plant. When methyl salicylate and propyl gallate were mixed individually with MJ, neither inhibited MJ-induced nicotine synthesis, which suggests that the inhibitors block jasmonate synthesis or release from stored pools and not its effects. Linolenic acid or its methyl ester applied to undamaged plants or damaged plants (to either damaged or undamaged leaves) or to the roots of hydroponically growing plants did not induce nicotine accumulation or increase nicotine accumulation above levels found in damaged plants. Similarly, traumatic acid, linoleic acid, and abscisic acid did not induce nicotine accumulations. Methyl dihydrojasmonate, which is biosynthetically derived from linoleic acid, had 12–56% of the nicotine-inducing acitivity of MJ when added to the roots of hydroponically grown plants. The signal transduction pathway mediating wound-induced nicotine production therefore shares many features of the pathway eliciting wound-induced proteinase inhibitor production but differs in not being regulated at the lipase step in jasmonic acid production and not being responsive to abscisic acid.  相似文献   
54.
We present a visual analytics system to understand the operation data of a company, GAStech, from IEEE VAST Challenge 2016. The data include proximity data recording the locations and movements of employees, and heating, ventilation, and air conditioning (HVAC) data recording the environmental conditions in the building. Analyzing the data to detect the suspicious behaviors of some disgruntled employees is of special interest. Our system provides coordinated multiple views to visualize the proximity data and the HVAC data over time. Visual hints and comparisons are designed for users to identify abnormal patterns and compare them. Furthermore, the system automatically detects and correlates the anomalies in the data. We provide use cases to demonstrate the effectiveness of our system.  相似文献   
55.
56.
We propose a uniform method to encode various types of trees succinctly. These families include ordered (ordinal), k-ary (cardinal), and unordered (free) trees. We will show the approach is intrinsically suitable for obtaining entropy-based encodings of trees (such as the degree-distribution entropy). Previously-existing succinct encodings of trees use ad hoc techniques to encode each particular family of trees. Additionally, the succinct encodings obtained using the uniform approach improve upon the existing succinct encodings of each family of trees; in the case of ordered trees, it simplifies the encoding while supporting the full set of navigational operations. It also simplifies the implementation of many supported operations. The approach applied to k-ary trees yields a succinct encoding that supports both cardinal-type operations (e.g. determining the child label i) as well as the full set of ordinal-type operations (e.g. reporting the number of siblings to the left of a node). Previous work on succinct encodings of k-ary trees does not support both types of operations simultaneously (Benoit et al. in Algorithmica 43(4):275–292, 2005; Raman et al. in ACM-SIAM Symposium on Discrete Algorithms (SODA), pp. 233–242, 2002). For unordered trees, the approach achieves the first succinct encoding. The approach is based on two recursive decompositions of trees into subtrees. Recursive decomposition of a structure into substructures is a common technique in succinct encodings and has even been used to encode (ordered) trees (Geary et al. in ACM Trans. Algorithms 2(4):510–534, 2006; He et al. in ICALP, pp. 509–520, 2007) and dynamic binary trees (Munro et al. in ACM-SIAM Symposium on Discrete Algorithms (SODA), pp. 529–536, 2001; Storm in Representing dynamic binary trees succinctly, Master’s thesis, 2000). The main distinction of the approach in this paper is that a tree is decomposed into subtrees in a manner that the subtrees are maximally isolated from each other. This intermediate decomposition result is interesting in its own right and has proved useful in other applications (Farzan et al. in ICALP (1), pp. 451–462, 2009; Farzan and Munro in ICALP (1), pp. 439–450, 2009; Farzan and Kamali in ICALP, 2011).  相似文献   
57.
We propose a novel regression based framework that uses online learned shape information to reconstruct occluded object contours. Our key insight is to regress the global, coarse, properties of shape from its local properties, i.e. its details. We do this by representing shapes using their 2D discrete cosine transforms and by regressing low frequency from high frequency harmonics. We learn this regression model using Locally Weighted Projection Regression which expedites online, incremental learning. After sufficient observation of a set of unoccluded shapes, the learned model can detect occlusion and recover the full shapes from the occluded ones. We demonstrate the ideas using a level-set based tracking system that provides shape and pose, however, the framework could be embedded in any segmentation-based tracking system. Our experiments demonstrate the efficacy of the method on a variety of objects using both real data and artificial data.  相似文献   
58.
UAV Path Following in Windy Urban Environments   总被引:2,自引:0,他引:2  
This paper considers UAV path following in cluttered environments under windy conditions. Unstructured wind patterns in cluttered environments can make path following difficult resulting in high errors and possibly collisions with buildings. Combining a pursuit guidance law philosophy with a line-of-sight guidance law, we develop a novel guidance law that has low computational complexity and can track straight line paths, circular paths, a combination of both and waypaths accurately in the presence of wind blowing as high as fifty percent of the UAV’s air speed. Performance of the guidance law is demonstrated through numerical simulations.  相似文献   
59.
介绍了超临界流体技术和微孔聚合物的概念及优点。着重介绍了超临界流体技术在微孔聚合物制备中的应用及发展状况,并简单介绍了制备微孔聚合物的影响因素,最后阐述了对超临界流体技术的展望和建议。  相似文献   
60.
Edward G. Smith  Ian D. Robb 《Polymer》1974,15(11):713-716
These investigations are concerned with water-polymer interactions in polymer latices. It is known that water can act as a plasticizer for many solid polymers and cause a reduction in the glass transition temperature, Tg, of the amorphous regions. Experiments were carried out to determine whether pulsed n.m.r. techniques could be used to study the Tg of a polymer suspension and hence the influence of water and electrolyte on it. From T1 and T2 proton relaxation measurements as a function of temperature on polystyrene latex systems it was shown that the presence of water lowers the Tg of the polymer particles (by about 10°C), the effect being slightly greater in the presence of concentrated electrolyte. The extent of electrolyte penetration into the particles was deduced by studying relaxation as a function of particle diameter in latices containing paramagnetic Mn2+ ions. Using simple theories of relaxation and spin diffusion it was concluded that for all but the smallest particles electrolyte penetration is restricted to a very thin shell of the order of 1 nm. These conclusions were supported by the results of similar measurements on PTFE particles.  相似文献   
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