干式接地变压器的故障分析

本文介绍两台干式接地变压器相继故障,通过事故象征,进行全面分析,由于制造工艺欠佳等原因,造成运行中高压侧绕组匝间短路,确定了产品故障的根本原因。     

覆膜滤料用聚四氟乙烯微孔膜的制备及其性能研究

针对市场上常用4种SSG范围的聚四氟乙烯(polytetrafluoroethylene,简称PTFE)树脂原料,采用双向拉伸法制备PTFE微孔膜,分析微孔膜性能的差异,并确定最适用于覆膜滤料用PTFE树脂原料.分析了不同分子量PTFE树脂原料的相对标准密度(SSG)、粒径、挤出压力和含水率等参数,采用不同分子量树脂原料来制备PTFE微孔膜,并表征PTFE微孔膜力学、厚度、结晶度、孔径、孔隙率和透气性能.研究表明:SSG的大小会影响PTFE微孔膜的力学性能(最大力、断裂伸长率)和孔结构(孔径、孔隙率),随SSG的增大呈现先上升后下降的趋势,在2.170～2.189范围内达到最优;结晶度与SSG的大小成正相关,而微孔膜透气性能主要与其孔结构有关,与孔径和孔隙率的变化趋势具有一致性.得出结论:PTFE树脂原料SSG分布在2.170～2.189范围时,制备的PTFE微孔膜最适用于覆膜滤料领域.     

考虑有功-无功协同优化的风场、光伏电站储能系统容量配置研究

为促进配网对风电、光伏的消纳,减少因高渗透率的分布式电源导致的电压波动,构建了以储能投资成本、购电成本、弃风弃光成本和网损成本最小为目标的蓄电池储能系统容量优化配置模型.首先,利用具有四象限运行特性的储能系统、有载调压变压器、分组投切电容器组对配网的有功无功进行协同优化.然后,采用融合时空关联特性的极限场景集描述可再生能源出力,使用大M法和二阶锥松弛技术将上述模型转化为混合整数线性规划问题,求解得到储能最优容量配置和有功-无功协同优化策略.最后,以IEEE-33节点系统为例进行分析.仿真结果表明,所提模型和方法能够提高配电网的电压质量和风电、光伏的消纳水平.     

核电厂棒电源发电机滑环的更换

秦二厂#2机组棒电源发电机已连续运行近16年,在最近一次解体检修时,测量发现发电机滑环外径接近最小要求尺寸,需对滑环整体进行更换处理.因为滑环和转轴固定方式特殊,且新滑环没有螺纹孔,所以设计出一种专用工具,以安全有效地对滑环实施更换,并提高了新滑环安装的准确性.     

基于区块链的分布式光伏就地消纳交易模式研究

目前配电网中分布式光伏发电渗透率越来越高,利用区块链技术的去中心化、难篡改等特点,有助于分布式发电就地或就近消纳,提高配电网运行的经济性。提出了一种基于区块链的光伏就地消纳交易模式,建立了光伏发电用户和分布式光伏聚合商的效益函数,运用Stackelberg博弈模型确定内部电价,通过边缘计算制定最优用电计划,设计了基于信誉值的就地消纳交易机制,对就地消纳程度低的用户进行惩罚,鼓励用户通过可时移负荷消纳光伏出力。配电网仿真结果表明,在采用区块链的交易模式下,配电网的就地消纳情况得到改善,用户的综合效益得到提升。     

硅烷偶联剂种类对胎面胶性能的影响

研究硅烷偶联剂种类对胎面胶各项性能的影响。结果表明：与使用通用型多硫硅烷偶联剂的胶料相比,使用巯基烷氧基硅烷偶联剂的胶料滞后损失降低,耐磨性能提高,其他性能有所下降;使用高反应活性巯基硅烷偶联剂的胶料具有较低的滚动阻力,但加工困难,物理性能较差;硫代羧酸酯类硅烷偶联剂具有优异的综合性能,应用于胎面胶中在保持其他性能的情况下可降低轮胎的滚动阻力,同时具有较好的湿地制动性能。     

Soluble Prokaryotic Overexpression and Purification of Human GM-CSF Using the Protein Disulfide Isomerase b′a′ Domain

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a member of the colony-stimulating factor (CSF) family, which functions to enhance the proliferation and differentiation of hematopoietic stem cells and other hematopoietic lineages such as neutrophils, dendritic cells, or macrophages. These proteins have thus generated considerable interest in clinical therapy research. A current obstacle to the prokaryotic production of human GM-CSF (hGM-CSF) is its low solubility when overexpressed and subsequent complex refolding processes. In our present study, the solubility of hGM-CSF was examined when combined with three N-terminal fusion tags in five E. coli strains at three different expression temperatures. In the five E. coli strains BL21 (DE3), ClearColi BL21 (DE3), LOBSTR, SHuffle T7 and Origami2 (DE3), the hexahistidine-tagged hGM-CSF showed the best expression but was insoluble in all cases at each examined temperature. Tagging with the maltose-binding protein (MBP) and the b′a′ domain of protein disulfide isomerase (PDIb′a′) greatly improved the soluble overexpression of hGM-CSF at 30 °C and 18 °C. The solubility was not improved using the Origami2 (DE3) and SHuffle T7 strains that have been engineered for disulfide bond formation. Two conventional chromatographic steps were used to purify hGM-CSF from the overexpressed PDIb′a′-hGM-CSF produced in ClearColi BL21 (DE3). In the experiment, 0.65 mg of hGM-CSF was isolated from a 0.5 L flask culture of these E. coli and showed a 98% purity by SDS-PAGE analysis and silver staining. The bioactivity of this purified hGM-CSF was measured at an EC₅₀ of 16.4 ± 2 pM by a CCK8 assay in TF-1 human erythroleukemia cells.     

Activation of Nrf2/HO-1 by Peptide YD1 Attenuates Inflammatory Symptoms through Suppression of TLR4/MYyD88/NF-κB Signaling Cascade

In this study, we investigate the immunomodulatory effects of a novel antimicrobial peptide, YD1, isolated from Kimchi, in both in vitro and in vivo models. We establish that YD1 exerts its anti-inflammatory effects via up-regulation of the Nrf2 pathway, resulting in the production of HO-1, which suppresses activation of the NF-κB pathway, including the subsequent proinflammatory cytokines IL-1β, IL-6, and TNF-α. We also found that YD1 robustly suppresses nitric oxide (NO) and prostaglandin E2 (PGE₂) production by down-regulating the expression of the upstream genes, iNOS and COX-2, acting as a strong antioxidant. Collectively, YD1 exhibits vigorous anti-inflammatory and antioxidant activity, presenting it as an interesting potential therapeutic agent.